| Cell clones . | Phenotypea . | Allele A (expressed)b . | Allele B (silent)b . |
|---|---|---|---|
| Single deletion | |||
| L1PA2_3.05 | DRT | 96,206,086–96,212,320 | Wild type |
| L1PA2_94.04 | Normal | Wild type | 96,206,107–96,212,320 |
| L1PA2_p3.15 | Normal | Wild type | 96,206,090–96,212,321 |
| L1PA2_p3.16 | Normal | Wild type | 96,206,090–96,212,321 |
| Single inversion | |||
| L1PA2_p3.18 | DRT | Left junction: (+)96,206,092–(−) 96,212,319 | Wild type |
| L1PA2_p3.24 | DRT | Right junction: (−)96,206,109–AAATATTGGCC–(+)96,212,320c | Wild type |
| L1PA2_p3.25 | DRT | ||
| L1PA2-16Di_1B | Normal | Wild type | Left junction: (+)96,206,097–(−) 96,212,315d |
| L1PA2-16Di_1E | Normal | Right junction: (−)96,206,109–(+)96,212,320 | |
| L1PA2-16Di_2D | Normal | ||
| Deletion/inversion | |||
| L1PA2_p3.16.15.65 | DRT | Left junction: (+)96,206,092–(−)96,212,319e | 96,206,090–96,212,321 |
| Right junction: (−)96,206,090–(+)96,212,321 | |||
| L1PA2_p11 | DRT | 96,206,107–96,212,320 | Left junction: (+)96,207,107–(−) 96,212,319 |
| Right junction: (−)96,206108–(+) 96,212,320 | |||
| Double deletion | |||
| L1PA2_p3.16.15.44 | DRT | 96,206,107–96,212,332 | 96,206,090–96,212,321 |
| L1PA2_p3.16.15.45 | DRT | ||
| L1PA2_p3.16.15.61 | DRT | ||
| L1PA2_p3.16.15.63 | DRT |
| Cell clones . | Phenotypea . | Allele A (expressed)b . | Allele B (silent)b . |
|---|---|---|---|
| Single deletion | |||
| L1PA2_3.05 | DRT | 96,206,086–96,212,320 | Wild type |
| L1PA2_94.04 | Normal | Wild type | 96,206,107–96,212,320 |
| L1PA2_p3.15 | Normal | Wild type | 96,206,090–96,212,321 |
| L1PA2_p3.16 | Normal | Wild type | 96,206,090–96,212,321 |
| Single inversion | |||
| L1PA2_p3.18 | DRT | Left junction: (+)96,206,092–(−) 96,212,319 | Wild type |
| L1PA2_p3.24 | DRT | Right junction: (−)96,206,109–AAATATTGGCC–(+)96,212,320c | Wild type |
| L1PA2_p3.25 | DRT | ||
| L1PA2-16Di_1B | Normal | Wild type | Left junction: (+)96,206,097–(−) 96,212,315d |
| L1PA2-16Di_1E | Normal | Right junction: (−)96,206,109–(+)96,212,320 | |
| L1PA2-16Di_2D | Normal | ||
| Deletion/inversion | |||
| L1PA2_p3.16.15.65 | DRT | Left junction: (+)96,206,092–(−)96,212,319e | 96,206,090–96,212,321 |
| Right junction: (−)96,206,090–(+)96,212,321 | |||
| L1PA2_p11 | DRT | 96,206,107–96,212,320 | Left junction: (+)96,207,107–(−) 96,212,319 |
| Right junction: (−)96,206108–(+) 96,212,320 | |||
| Double deletion | |||
| L1PA2_p3.16.15.44 | DRT | 96,206,107–96,212,332 | 96,206,090–96,212,321 |
| L1PA2_p3.16.15.45 | DRT | ||
| L1PA2_p3.16.15.61 | DRT | ||
| L1PA2_p3.16.15.63 | DRT |
Replication timing was measured by BrdU incorporation into chromosomes. DRT, delayed replication timing.
Identities of affected alleles were determined by PCR and sequencing of the heterozygous SNP, rs9375937.
Chromosome 6 bases 96,206,093–96,206,108 were deleted and an 11-bp duplication was created.
Chromosome 6 bases 96,206,098–96,206,108 and 96,212,316–96,212,319 were deleted.
Chromosome 6 bases 96,206,091 and 96,212,320 were deleted.