| Process/protein complex . | Genes . | Telomeropathies . |
|---|---|---|
| Telomerase core components | TERC | DC, IPF, aplastic anemia, liver disease |
| TERT | DC, HHS, IPF, aplastic anemia, liver disease | |
| Telomerase biogenesis | DKC1 | DC, HHS, IPF, aplastic anemia |
| NOP10 | DC, IPF, aplastic anemia | |
| NHP2 | DC, IPF, aplastic anemia | |
| Telomerase trafficking | TCBA1 | DC |
| Shelterin components | TIN2 | DC, HHS |
| TPP1 | DC, HHS, aplastic anemia | |
| Telomeric DNA synthesis | RTEL1 | HHS, IPF |
| CTC1 | DC | |
| TERC RNA processing | PARN | DC, IPF |
| NAF1 | IPF |
| Process/protein complex . | Genes . | Telomeropathies . |
|---|---|---|
| Telomerase core components | TERC | DC, IPF, aplastic anemia, liver disease |
| TERT | DC, HHS, IPF, aplastic anemia, liver disease | |
| Telomerase biogenesis | DKC1 | DC, HHS, IPF, aplastic anemia |
| NOP10 | DC, IPF, aplastic anemia | |
| NHP2 | DC, IPF, aplastic anemia | |
| Telomerase trafficking | TCBA1 | DC |
| Shelterin components | TIN2 | DC, HHS |
| TPP1 | DC, HHS, aplastic anemia | |
| Telomeric DNA synthesis | RTEL1 | HHS, IPF |
| CTC1 | DC | |
| TERC RNA processing | PARN | DC, IPF |
| NAF1 | IPF |
The diseases found associated with the mutated genes are indicated (Calado et al., 2009a; Holohan et al., 2014; Glousker et al., 2015; Stanley and Armanios, 2015; Stanley et al., 2016).