Table 1.
Metabolic tests and associated inhibitors
Metabolite testTreatment 1Treatment 2
Glucose/Pyruvate dependence UK5099 Etomoxir + BPTES 
Glutamine dependence BPTES Etomoxir + UK5099 
Fatty acid dependence Etomoxir BPTES + UK5099 
Metabolite testTreatment 1Treatment 2
Glucose/Pyruvate dependence UK5099 Etomoxir + BPTES 
Glutamine dependence BPTES Etomoxir + UK5099 
Fatty acid dependence Etomoxir BPTES + UK5099 

Dependency (%) = ([Baseline OCR-Target inhibitor OCR]/[Baseline OCR-All inhibitors OCR]) × 100%.

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