| C. elegans | S. cerevisiae | Mammals | Identified cargo proteins (species) | VIT-2 accumulation in the intestine |
|---|---|---|---|---|
| ile-1 | Emp46p/Emp47p | ERGIC-53 | Coagulation factors V and VIII, Cathepsin C and Z, α1-antitrypsin (Hs) | − |
| sel-9 | Emp24p | p24β | Gas1p (Sc) | − |
| rer-1 | Rer1p | Rer1 | Sec12p, Sec63p, Sec71p, Mns1p (Sc) | − |
| sft-4 | Erv29p | Surf4 | gp-α-factor, CPY, proteinase A (Sc) | +++ |
| Emp46p/Emp47p | ERGIC-53 | Coagulation factors V and VIII, Cathepsin C and Z, α1-antitrypsin (Hs) | − | |
| Emp24p | p24β | Gas1p (Sc) | − | |
| Rer1p | Rer1 | Sec12p, Sec63p, Sec71p, Mns1p (Sc) | − | |
| Erv29p | Surf4 | gp-α-factor, CPY, proteinase A (Sc) | +++ |
Hs, Homo sapiens; Sc, Saccharomyces cerevisiae.
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