| Category | Count | P |
|---|---|---|
| Annotation cluster 1 | Enrichment score: 4.33 | |
| Focal adhesiona (KEGG_PATHWAY) | 18 | 5.1E−6 |
| Regulation of actin cytoskeletona (KEGG_PATHWAY) | 18 | 8.0E−6 |
| Proteoglycans in cancer (KEGG_PATHWAY) | 13 | 2.5E−3 |
| Annotation cluster 2 | Enrichment score: 3.42 | |
| Cadherin binding involved in cell–cell adhesiona (GOTERM_MF) | 18 | 8.1E−5 |
| Cell–cell adherens junctiona (GOTERM_CC) | 19 | 1.1E−4 |
| Cell–cell adhesiona (GOTERM_BP) | 11 | 6.3E−3 |
| Annotation cluster 3 | Enrichment score: 2.58 | |
| Outflow tract morphogenesis (GOTERM_BP) | 9 | 1.5E−5 |
| Palate development (GOTERM_BP) | 6 | 3.2E−2 |
| Heart looping (GOTERM_BP) | 5 | 4.0E−2 |
| Annotation cluster 4 | Enrichment score: 2.05 | |
| Differentiation (UP_KEYWORDS) | 24 | 2.1E−3 |
| Neurogenesis (UP_KEYWORDS) | 12 | 6.4E−3 |
| Nervous system development (GOTERM_BP) | 14 | 5.2E−2 |
| Annotation cluster 5 | Enrichment score: 1.90 | |
| GTP-bindinga (UP_KEYWORDS) | 15 | 3.6E−3 |
| GTPase activitya (GOTERM_MF) | 12 | 4.4E−3 |
| Small GTPase mediated signal transductiona (GOTERM_BP) | 12 | 1.1E−2 |
| Nucleotide phosphate-binding region:GTPa (UP_SEQ_FEATURE) | 15 | 1.2E−2 |
| GTP bindinga (GOTERM_MF) | 16 | 1.5E−2 |
| Small GTP-binding protein domaina (INTERPRO) | 9 | 1.5E−2 |
| P-loop containing nucleoside triphosphate hydrolasea (INTERPRO) | 24 | 1.1E−1 |
| Annotation cluster 6 | Enrichment score: 1.81 | |
| Actin-bindinga (UP_KEYWORDS) | 13 | 2.6E−3 |
| Actin filament bindinga (GOTERM_MF) | 8 | 2.1E−2 |
| Brush border (GOTERM_CC) | 6 | 2.2E−2 |
| Actin bindinga (GOTERM_MF) | 13 | 5.1E−2 |
| Annotation cluster 7 | Enrichment score: 1.76 | |
| Tight junctiona (KEGG_PATHWAY) | 9 | 1.4E−3 |
| Bicellular tight junctiona (GOTERM_CC) | 6 | 1.9E−2 |
| Tight junctiona (UP_KEYWORDS) | 5 | 2.0E−1 |
| Enrichment score: 4.33 | ||
| Focal adhesion | 18 | 5.1E−6 |
| Regulation of actin cytoskeleton | 18 | 8.0E−6 |
| Proteoglycans in cancer (KEGG_PATHWAY) | 13 | 2.5E−3 |
| Enrichment score: 3.42 | ||
| Cadherin binding involved in cell–cell adhesion | 18 | 8.1E−5 |
| Cell–cell adherens junction | 19 | 1.1E−4 |
| Cell–cell adhesion | 11 | 6.3E−3 |
| Enrichment score: 2.58 | ||
| Outflow tract morphogenesis (GOTERM_BP) | 9 | 1.5E−5 |
| Palate development (GOTERM_BP) | 6 | 3.2E−2 |
| Heart looping (GOTERM_BP) | 5 | 4.0E−2 |
| Enrichment score: 2.05 | ||
| Differentiation (UP_KEYWORDS) | 24 | 2.1E−3 |
| Neurogenesis (UP_KEYWORDS) | 12 | 6.4E−3 |
| Nervous system development (GOTERM_BP) | 14 | 5.2E−2 |
| Enrichment score: 1.90 | ||
| GTP-binding | 15 | 3.6E−3 |
| GTPase activity | 12 | 4.4E−3 |
| Small GTPase mediated signal transduction | 12 | 1.1E−2 |
| Nucleotide phosphate-binding region:GTP | 15 | 1.2E−2 |
| GTP binding | 16 | 1.5E−2 |
| Small GTP-binding protein domain | 9 | 1.5E−2 |
| P-loop containing nucleoside triphosphate hydrolase | 24 | 1.1E−1 |
| Enrichment score: 1.81 | ||
| Actin-binding | 13 | 2.6E−3 |
| Actin filament binding | 8 | 2.1E−2 |
| Brush border (GOTERM_CC) | 6 | 2.2E−2 |
| Actin binding | 13 | 5.1E−2 |
| Enrichment score: 1.76 | ||
| Tight junction | 9 | 1.4E−3 |
| Bicellular tight junction | 6 | 1.9E−2 |
| Tight junction | 5 | 2.0E−1 |
Annotation cluster defines a group of terms having similar biological functions. The enrichment score is the rank of the annotation cluster based on its significance within the dataset tested. The count column refers to number of genes involved in the same category.
Annotation cluster categories related to barrier function.
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