Table 1. Examples of changes observed in... | Rockefeller University Press

Table 1.

Examples of changes observed in the differentiation proteome

TriTrypDB ID	Description	Log₂ T3C/T3N protein	Log₂ T3C/T3N phosphorylation^{^a}	Classification
Tb927.8.1640	MSP-B, major surface protease	+3.67	—	Surface
Tb927.7.6850	TS, trans-sialidase	+1.68	—	Surface
Tb927.10.11220	PSSA-2, procyclic form surface protein	+1.45	—	Surface
Tb927.1.2100	Calpain-like cysteine peptidase	+0.36	S81 +4.25; S366 +3.23; T365 +2.72; S95 +2.64	Surface
Tb927.11.17870	VSG, variant surface glycoprotein	−1.75	—	Surface
Tb927.5.370	ISG75, 75-kD invariant surface glycoprotein	−2.09	—	Surface
Tb927.10.8530	THT2A, glucose transporter	+3.05	T526 +2.83	Metabolism
Tb927.10.15410	gMDH, glycosomal malate dehydrogenase	+2.43	—	Metabolism
Tb927.10.6950	Sterol 24-C-methyltransferase	+2.12	—	Metabolism
Tb927.1.710	PGKB, phosphoglycerate kinase B	−3.58	—	Metabolism
Tb927.1.2600	PUF9, pumilio RNA binding protein	−1.98		Cell cycle
Tb927.11.11770	eIF4e, eukaryotic translation initiation factor 4e	+0.20	T159 +2.89	Cell cycle
Tb927.11.1820	eIF2b, eukaryotic translation initiation factor 2b	+0.19	S126 +2.57; T127 +2.57	Cell cycle
Tb927.9.6100	PIP39, PTP1-interacting protein	+2.50	—	Signaling
Tb927.7.5940	PAD2, protein associated with differentiation 2	+0.05	T577 -4.46; T587 −3.65	Signaling
Tb927.7.5990	PAD7, protein associated with differentiation 7	−0.15	T584 +7.01; S580 +3.44; S582 +2.71	Signaling
Tb927.6.3490	ZFP1, zinc finger protein 1	—	S18 +2.81; S16 +2.56	Signaling

TriTrypDB ID	Description	Log₂ T3C/T3N protein	Log₂ T3C/T3N phosphorylation^a	Classification
Tb927.8.1640	MSP-B, major surface protease	+3.67	—	Surface
Tb927.7.6850	TS, trans-sialidase	+1.68	—	Surface
Tb927.10.11220	PSSA-2, procyclic form surface protein	+1.45	—	Surface
Tb927.1.2100	Calpain-like cysteine peptidase	+0.36	S81 +4.25; S366 +3.23; T365 +2.72; S95 +2.64	Surface
Tb927.11.17870	VSG, variant surface glycoprotein	−1.75	—	Surface
Tb927.5.370	ISG75, 75-kD invariant surface glycoprotein	−2.09	—	Surface
Tb927.10.8530	THT2A, glucose transporter	+3.05	T526 +2.83	Metabolism
Tb927.10.15410	gMDH, glycosomal malate dehydrogenase	+2.43	—	Metabolism
Tb927.10.6950	Sterol 24-C-methyltransferase	+2.12	—	Metabolism
Tb927.1.710	PGKB, phosphoglycerate kinase B	−3.58	—	Metabolism
Tb927.1.2600	PUF9, pumilio RNA binding protein	−1.98		Cell cycle
Tb927.11.11770	eIF4e, eukaryotic translation initiation factor 4e	+0.20	T159 +2.89	Cell cycle
Tb927.11.1820	eIF2b, eukaryotic translation initiation factor 2b	+0.19	S126 +2.57; T127 +2.57	Cell cycle
Tb927.9.6100	PIP39, PTP1-interacting protein	+2.50	—	Signaling
Tb927.7.5940	PAD2, protein associated with differentiation 2	+0.05	T577 -4.46; T587 −3.65	Signaling
Tb927.7.5990	PAD7, protein associated with differentiation 7	−0.15	T584 +7.01; S580 +3.44; S582 +2.71	Signaling
Tb927.6.3490	ZFP1, zinc finger protein 1	—	S18 +2.81; S16 +2.56	Signaling

For proteins with multiple phosphorylation sites, only those with the largest changes are given; see Table S3 for full details. Missing values were either not observed or not quantified.

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