Table 2.
Genes repressed by nuclear calcium signaling (i.e., up-regulated by CaMBP4) with a function in promoting anergy
SignalingInhibitors of MAPKs pathwayE3 ubiquitin ligasesProteasome
Fas PTPN7 RNF19B PSMA6 
CD97 PTPN22 CBL PSMA1 
GDI1 PTPN6 Transcription PSMC6 
RGS16 DUSP6 NFATC1 PSMD12 
GEM DUSP5 EGR1 PSMD6 
Sh2D2A DUSP2 EGR2 PSMB2 
Receptors DUSP8 EGR3 PSMC1 
FasL DUSP1 STAT4 PSMC4 
CD44 DUSP4 STAT6 PSMA3 
IL7R DGKα Jarid2 Other functions 
TNFRSF4 Inhibitors of proliferation Nr4a2 Actn4 
ICOS-LG BTG2 Nr4a3 CCRN4L 
Inhibitory receptors IER5 IRF4 Hif1a 
PDCD1 (PD1) CDKN1A (P21Zfp36 S100a 
CTLA4 GADD45B  Stx11 
 PFN1   
 CDKN1B (p27 kip  
SignalingInhibitors of MAPKs pathwayE3 ubiquitin ligasesProteasome
Fas PTPN7 RNF19B PSMA6 
CD97 PTPN22 CBL PSMA1 
GDI1 PTPN6 Transcription PSMC6 
RGS16 DUSP6 NFATC1 PSMD12 
GEM DUSP5 EGR1 PSMD6 
Sh2D2A DUSP2 EGR2 PSMB2 
Receptors DUSP8 EGR3 PSMC1 
FasL DUSP1 STAT4 PSMC4 
CD44 DUSP4 STAT6 PSMA3 
IL7R DGKα Jarid2 Other functions 
TNFRSF4 Inhibitors of proliferation Nr4a2 Actn4 
ICOS-LG BTG2 Nr4a3 CCRN4L 
Inhibitory receptors IER5 IRF4 Hif1a 
PDCD1 (PD1) CDKN1A (P21Zfp36 S100a 
CTLA4 GADD45B  Stx11 
 PFN1   
 CDKN1B (p27 kip  

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