| Process . | Protein name . | Curvature . | Molecular mechanism . | Figure . | References . |
|---|---|---|---|---|---|
| Appressorium | Rvs167 | Positive | BAR domain, scaffolding | 3 A | Dagdas et al., 2012 |
| Appressorium | Septins | Positive | Oligomerization, scaffolding | 3 C | Bezanilla et al., 2015; Bridges et al., 2016 |
| Caveolae | Caveolin | Positive | Oligomerization, hairpin insertion | 2 C | Monier et al., 1995 |
| Caveolae | Cavins | Positive | Oligomerization, clustering | 2 C | Hansen et al., 2009 |
| Caveolae | EHD2 | Positive | Oligomerization, GTPase | 3 C | Daumke et al., 2007; Morén et al., 2012 |
| Caveolae | PACSIN2 | Positive | BAR domain, scaffolding | 3 A | Senju et al., 2011 |
| Endocytosis, clathrin mediated | Actin | Positive, negative | Substrate for motor proteins, membrane pulling, polymerization pushing against the membrane, ATPase | 3 G & H | Collins et al., 2011; Lewellyn et al., 2015 |
| Endocytosis, clathrin mediated | Amphiphysin | Positive | Amphipathic helix, bilayer asymmetry, BAR domain scaffolding and oligomerization | 2 E | Peter et al., 2004; Isas et al., 2015 |
| Endocytosis, clathrin mediated | CALM | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Miller et al., 2015 |
| Endocytosis, clathrin mediated | CIP4 | Positive | F-BAR domain, oligomerization, scaffolding | 3 A & C | Frost et al., 2008 |
| Endocytosis, clathrin mediated | Clathrin | Positive | Scaffolding via oligomerization, crowding | 3 C & E | Fotin et al., 2004; Avinoam et al., 2015 |
| Endocytosis, clathrin mediated | Dynamin | Positive | Oligomerization, scaffolding, GTPase | 3 C | Chappie et al., 2011; Morlot et al., 2012 |
| Endocytosis, clathrin mediated | Epsin | Positive | Amphipathic helix, bilayer asymmetry, crowding | 2 D, 3 E | Ford et al., 2002; Stachowiak et al., 2012, 2013; Busch et al., 2015 |
| Endocytosis, clathrin mediated | FCHo1/2 | Positive | F-BAR domain, scaffolding | 3 A | Henne et al., 2007, 2010 |
| Endocytosis, Shiga toxin uptake | Gb3 | Negative | Lipid receptor, clustering, crowding | 2 C | Römer et al., 2007 |
| Endocytosis, Shiga toxin uptake | Shiga toxin | Negative | Clustering, crowding | 2 C | Römer et al., 2007 |
| Endosomal tubules | Dynein | Positive | Microtubule motor, pulling of membrane compartments, ATPase | 3 H | Day et al., 2015 |
| Endosomal tubules | Kinesin | Positive | Microtubule motor, pulling of membrane compartments, ATPase | 3 H | Roux et al., 2002; Delevoye et al., 2014 |
| Endosomal tubules | SNX1 | Positive | BAR domain, scaffolding, oligomerization | 3 A | Carlton et al., 2004 |
| ER shaping | Actin | Positive | Substrate for motor proteins, membrane pulling, ATPase | 3 H | Quader et al., 1989; Liebe and Menzel, 1995; Estrada et al., 2003; Sparkes et al., 2009 |
| ER shaping | Atlastins | Positive | Hydrophobic domain insertion, clustering, GTPase | 2 C | Hu et al., 2009 |
| ER shaping | DP1/YOP1 | Positive | Insertion of wedge-shaped membrane-binding domain | 2 C | Voeltz et al., 2006 |
| ER shaping | Microtubules | Positive | Substrate for motor proteins, membrane pulling | 3 H | Waterman-Storer and Salmon, 1998 |
| ER shaping | Myosin | Positive | Actin motor protein, ER tubule pulling, ATPase | 3 H | Estrada et al., 2003 |
| ER shaping | RTNs | Positive | Insertion of hairpin membrane-binding domain | 2 C | Voeltz et al., 2006 |
| ER shaping | Sey1 | Positive | Hydrophobic domain insertion, clustering | 2 C | Hu et al., 2009 |
| ER, anterograde trafficking | COPII | Positive | Scaffolding via oligomerization | 3 C | Lee et al., 2005; Manneville et al., 2008 |
| ER, anterograde trafficking | Sar1 | Positive | Amphipathic helix, dimerization, scaffolding | 2 D & F; 3 C | Lee et al., 2005; Beck et al., 2008; Krauss et al., 2008 |
| ER, anterograde trafficking | Sec12/31 | Positive | Oligomerization, scaffolding, crowding | 3 C & E | Copic et al., 2012 |
| ER, anterograde trafficking | Sec23/24 | Positive | Curved membrane-binding domain, scaffolding | 3 A | Bi et al., 2002 |
| Filopodia | Actin | Negative | Polymerization within membrane compartment, membrane pushing | 3 F | Liu et al., 2008 |
| Filopodia | Dopamine transporter | Negative | Shaped transmembrane domain | 2 B | Caltagarone et al., 2015 |
| Filopodia | IRSp53 | Negative | I-BAR domain, scaffolding | 3 B | Mattila et al., 2007 |
| Filopodia | MIM | Negative | I-BAR domain, scaffolding | 3 B | Mattila et al., 2007; Saarikangas et al., 2009, 2015 |
| Filopodia | srGAP2 | Negative | F-BAR domain, scaffolding | 3 B | Guerrier et al., 2009 |
| Golgi, retrograde trafficking | Arf1 | Positive | Amphipathic helix, dimerization, scaffolding via oligomerization | 2 D & F; 3 C | Lee et al., 2005; Beck et al., 2008; Krauss et al., 2008 |
| Golgi, retrograde trafficking | ArfGAP1 | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Bigay et al., 2003; Antonny et al., 2005 |
| Golgi, retrograde trafficking | COPI | Positive | Scaffolding via oligomerization | 3 C | Lee et al., 2005; Manneville et al., 2008 |
| Mitochondrial cristae | F1Fo-ATPase | Positive | Dimerization, shaping via transmembrane domain | 2 B & C | Jiko et al., 2015 |
| Mitochondrial cristae | Mic10 | Positive | Insertion of hairpin transmembrane domain, clustering | 2 C | Harner et al., 2011; Barbot et al., 2015 |
| MVBs | ESCRT-III | Negative | Scaffolding, helical oligomerization | 3 D | Hanson et al., 2008; Henne et al., 2012; Cashikar et al., 2014; McCullough et al., 2015 |
| MVBs | Lysobisphosphatidic acid | Negative | Lipid shape | 2 A | Matsuo et al., 2004 |
| Nuclear pore | Nup53 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Vollmer et al., 2012 |
| Nuclear pore | Nup133 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Doucet and Hetzer, 2010 |
| Nuclear pore | Nup153 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Mészáros et al., 2015; Vollmer et al., 2015 |
| Thylakoid shaping | CURT1 | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Armbruster et al., 2013 |
| Process . | Protein name . | Curvature . | Molecular mechanism . | Figure . | References . |
|---|---|---|---|---|---|
| Appressorium | Rvs167 | Positive | BAR domain, scaffolding | 3 A | Dagdas et al., 2012 |
| Appressorium | Septins | Positive | Oligomerization, scaffolding | 3 C | Bezanilla et al., 2015; Bridges et al., 2016 |
| Caveolae | Caveolin | Positive | Oligomerization, hairpin insertion | 2 C | Monier et al., 1995 |
| Caveolae | Cavins | Positive | Oligomerization, clustering | 2 C | Hansen et al., 2009 |
| Caveolae | EHD2 | Positive | Oligomerization, GTPase | 3 C | Daumke et al., 2007; Morén et al., 2012 |
| Caveolae | PACSIN2 | Positive | BAR domain, scaffolding | 3 A | Senju et al., 2011 |
| Endocytosis, clathrin mediated | Actin | Positive, negative | Substrate for motor proteins, membrane pulling, polymerization pushing against the membrane, ATPase | 3 G & H | Collins et al., 2011; Lewellyn et al., 2015 |
| Endocytosis, clathrin mediated | Amphiphysin | Positive | Amphipathic helix, bilayer asymmetry, BAR domain scaffolding and oligomerization | 2 E | Peter et al., 2004; Isas et al., 2015 |
| Endocytosis, clathrin mediated | CALM | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Miller et al., 2015 |
| Endocytosis, clathrin mediated | CIP4 | Positive | F-BAR domain, oligomerization, scaffolding | 3 A & C | Frost et al., 2008 |
| Endocytosis, clathrin mediated | Clathrin | Positive | Scaffolding via oligomerization, crowding | 3 C & E | Fotin et al., 2004; Avinoam et al., 2015 |
| Endocytosis, clathrin mediated | Dynamin | Positive | Oligomerization, scaffolding, GTPase | 3 C | Chappie et al., 2011; Morlot et al., 2012 |
| Endocytosis, clathrin mediated | Epsin | Positive | Amphipathic helix, bilayer asymmetry, crowding | 2 D, 3 E | Ford et al., 2002; Stachowiak et al., 2012, 2013; Busch et al., 2015 |
| Endocytosis, clathrin mediated | FCHo1/2 | Positive | F-BAR domain, scaffolding | 3 A | Henne et al., 2007, 2010 |
| Endocytosis, Shiga toxin uptake | Gb3 | Negative | Lipid receptor, clustering, crowding | 2 C | Römer et al., 2007 |
| Endocytosis, Shiga toxin uptake | Shiga toxin | Negative | Clustering, crowding | 2 C | Römer et al., 2007 |
| Endosomal tubules | Dynein | Positive | Microtubule motor, pulling of membrane compartments, ATPase | 3 H | Day et al., 2015 |
| Endosomal tubules | Kinesin | Positive | Microtubule motor, pulling of membrane compartments, ATPase | 3 H | Roux et al., 2002; Delevoye et al., 2014 |
| Endosomal tubules | SNX1 | Positive | BAR domain, scaffolding, oligomerization | 3 A | Carlton et al., 2004 |
| ER shaping | Actin | Positive | Substrate for motor proteins, membrane pulling, ATPase | 3 H | Quader et al., 1989; Liebe and Menzel, 1995; Estrada et al., 2003; Sparkes et al., 2009 |
| ER shaping | Atlastins | Positive | Hydrophobic domain insertion, clustering, GTPase | 2 C | Hu et al., 2009 |
| ER shaping | DP1/YOP1 | Positive | Insertion of wedge-shaped membrane-binding domain | 2 C | Voeltz et al., 2006 |
| ER shaping | Microtubules | Positive | Substrate for motor proteins, membrane pulling | 3 H | Waterman-Storer and Salmon, 1998 |
| ER shaping | Myosin | Positive | Actin motor protein, ER tubule pulling, ATPase | 3 H | Estrada et al., 2003 |
| ER shaping | RTNs | Positive | Insertion of hairpin membrane-binding domain | 2 C | Voeltz et al., 2006 |
| ER shaping | Sey1 | Positive | Hydrophobic domain insertion, clustering | 2 C | Hu et al., 2009 |
| ER, anterograde trafficking | COPII | Positive | Scaffolding via oligomerization | 3 C | Lee et al., 2005; Manneville et al., 2008 |
| ER, anterograde trafficking | Sar1 | Positive | Amphipathic helix, dimerization, scaffolding | 2 D & F; 3 C | Lee et al., 2005; Beck et al., 2008; Krauss et al., 2008 |
| ER, anterograde trafficking | Sec12/31 | Positive | Oligomerization, scaffolding, crowding | 3 C & E | Copic et al., 2012 |
| ER, anterograde trafficking | Sec23/24 | Positive | Curved membrane-binding domain, scaffolding | 3 A | Bi et al., 2002 |
| Filopodia | Actin | Negative | Polymerization within membrane compartment, membrane pushing | 3 F | Liu et al., 2008 |
| Filopodia | Dopamine transporter | Negative | Shaped transmembrane domain | 2 B | Caltagarone et al., 2015 |
| Filopodia | IRSp53 | Negative | I-BAR domain, scaffolding | 3 B | Mattila et al., 2007 |
| Filopodia | MIM | Negative | I-BAR domain, scaffolding | 3 B | Mattila et al., 2007; Saarikangas et al., 2009, 2015 |
| Filopodia | srGAP2 | Negative | F-BAR domain, scaffolding | 3 B | Guerrier et al., 2009 |
| Golgi, retrograde trafficking | Arf1 | Positive | Amphipathic helix, dimerization, scaffolding via oligomerization | 2 D & F; 3 C | Lee et al., 2005; Beck et al., 2008; Krauss et al., 2008 |
| Golgi, retrograde trafficking | ArfGAP1 | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Bigay et al., 2003; Antonny et al., 2005 |
| Golgi, retrograde trafficking | COPI | Positive | Scaffolding via oligomerization | 3 C | Lee et al., 2005; Manneville et al., 2008 |
| Mitochondrial cristae | F1Fo-ATPase | Positive | Dimerization, shaping via transmembrane domain | 2 B & C | Jiko et al., 2015 |
| Mitochondrial cristae | Mic10 | Positive | Insertion of hairpin transmembrane domain, clustering | 2 C | Harner et al., 2011; Barbot et al., 2015 |
| MVBs | ESCRT-III | Negative | Scaffolding, helical oligomerization | 3 D | Hanson et al., 2008; Henne et al., 2012; Cashikar et al., 2014; McCullough et al., 2015 |
| MVBs | Lysobisphosphatidic acid | Negative | Lipid shape | 2 A | Matsuo et al., 2004 |
| Nuclear pore | Nup53 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Vollmer et al., 2012 |
| Nuclear pore | Nup133 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Doucet and Hetzer, 2010 |
| Nuclear pore | Nup153 | Positive | Amphipathic helix, bilayer asymmetry | 2 F | Mészáros et al., 2015; Vollmer et al., 2015 |
| Thylakoid shaping | CURT1 | Positive | Amphipathic helix, bilayer asymmetry | 2 D | Armbruster et al., 2013 |