Table 1.
Composition of the MRGs
Gene nameFunctionConserved domains (PFAM)Reference
DDX28 Mitoribosome assembly DEAD; Helicase_C Antonicka and Shoubridge, 2015; Tu and Barrientos, 2015  
DHX30 Mitoribosome assembly DEAD; HA2; Helicase_C; OB_NTP_bind Wang and Bogenhagen, 2006; Antonicka and Shoubridge, 2015  
FASTK RNA processing FAST_1; FAST_2; RAP Jourdain et al., 2015  
FASTKD2 RNA processing; mitoribosome assembly FAST_1; FAST_2; RAP Antonicka and Shoubridge, 2015; Jourdain et al., 2015  
FASTKD5 RNA processing; mitoribosome assembly FAST_1; FAST_2; RAP Antonicka and Shoubridge, 2015  
FTSJ2a (MRM2) rRNA methylation FtsJ Lee et al., 2013  
GRSF1 RNA processing; mitoribosome assembly RRM6 (3x) Antonicka et al., 2013; Jourdain et al., 2013  
HSD17B10 (MRPP2) RNAse P - 5′ tRNA processing adh_short Jourdain et al., 2013; Bogenhagen et al., 2014  
KIAA0391 (MRPP3) RNAse P - 5′ tRNA processing PRORP Jourdain et al., 2013; Bogenhagen et al., 2014  
MRM1a rRNA methylation SpoU_methylase; SpoU_sub_bind Lee et al., 2013  
MTPAP (PAPD1) Poly(A) polymerase PAP_assoc Wilson et al., 2014  
PNPT1 (PNPase) RNA degradation; RNA processing KH_1; PNPase; RNase_PH; RNase_PH_C; S1 Borowski et al., 2013  
RNMTL1a (MRM3) rRNA methylation SpoU_methylase; SpoU_sub_bind Lee et al., 2013  
SUPV3L1 (hSuv3p) RNA degradation; RNA processing Helicase_C; SUV3_C Borowski et al., 2013  
TRMT10C (MRPP1) RNAse P - 5′ tRNA processing; tRNA methyltransferase tRNA_m1G_MT Jourdain et al., 2013; Bogenhagen et al., 2014  

The names, functions, and conserved domains of the proteins currently known to localize with MRGs are shown.

a

Reported to colocalize with foci adjacent to but distinct from nucleoids, which likely correspond to MRGs.

[ViewLarge]
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal