Table 1.
Sequences of siRNA used to knock down respective targets
TargetSequence 1Sequence 2Sequence 3Sequence 4
ADAM9 GCAAAGAGCUGUAUCAUGA GAGAUUAACUAGAGAAAGA GAACCAGACUGCUGUGAGA GCAGAUCUCUUACGUCAUC 
ADAM10 GAAGGAAGCUUUAGUCAUG CCCAAAGUCUCUCAUAUUA GCAGAGAGAUACAUUAAAG GAAUUGCCCUGAUCAUGUU 
ADAM17 GAAAGACACUUCAAUAUGG UAUGGGAACUCUUGGAUUA GGUAGCAGAUCAUCGAUUU UGACCGAGUUGAUGACAUA 
TSPAN5 GGAAUAACGUUUCUUGGAA GCGAUGCGGUGUGCCAUUU GAUGAUUGGAACCUAAAUA CAUAGGCAUUGCAUUGCUA 
TSPAN12 GGUCAGAUAUGGUUACUUU GAACGUUACUCGUCAUCUU GCGGUCAUCUUAACUUACU CAUACGAGCAGGAGGUUAU 
TSPAN14 CAGCUACAAUAUCGUCUUU GAACCUCAUUGACUCCCUU GAACAUCUGCCUGCUCAAG GGGAAUUCUUCGAGAGCAA 
TSPAN17 GAUCCGAGACCAACUUAAU ACAACAAUGUCAAAGCCUA GAAUACUGGUCUUGCUGUG UGACAGAUCUGGGCGGUCU 
CONTROL UAGCGACUAAACACAUCAA UAAGGCUAUGAAGAGAUAC AUGUAUUGGCCUGUAUUAG AUGAACGUGAAUUGCUCAA 

GE Healthcare siGENOME is a pool of four individual siRNAs. Sequences 5′- to -3′ for the individual siRNAs are listed for each target.

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