Table 1. Histological change of the mice... | Rockefeller University Press

Table 1.

Histological change of the mice scalp wound

Wound parameter	Day	Normoglycemic			Diabetic
		K14.Cre⁻.Foxo1^L/L	K14.Cre⁺.Foxo1^L/L	Cre⁺/Cre⁻	K14.Cre⁻.Foxo1^L/L	K14.Cre⁺.Foxo1^L/L	Cre⁺/Cre⁻
Epithelial gap (mm)	4	0.59 ± 0.27	1.76 ± 0.08^a	2.98	1.66 ± 0.08	1.01 ± 0.17^b	0.61
	7	0.35 ± 0.28	0.56 ± 0.36^a	1.60	1.52 ± 0.13	0.29 ± 0.18^b	0.19
Epithelial thickness (mm)	4	0.09 ± 0.01	0.06 ± 0.01^a	0.67	0.07 ± 0.01	0.10 ± 0.01^b	1.43
	7	0.08 ± 0.01	0.05 ± 0.01^a	0.63	0.06 ± 0.01	0.08 ± 0.01^b	1.33
Epithelial area (mm²)	4	0.21 ± 0.02	0.11 ± 0.02^a	0.52	0.17 ± 0.01	0.23 ± 0.02^b	1.35
	7	0.18 ± 0.01	0.10 ± 0.02^a	0.56	0.10 ± 0.01	0.16 ± 0.01^b	1.60

Wound parameter	Day	Normoglycemic			Diabetic
		K14.Cre⁻.Foxo1^L/L	K14.Cre⁺.Foxo1^L/L	Cre⁺/Cre⁻	K14.Cre⁻.Foxo1^L/L	K14.Cre⁺.Foxo1^L/L	Cre⁺/Cre⁻
Epithelial gap (mm)	4	0.59 ± 0.27	1.76 ± 0.08^a	2.98	1.66 ± 0.08	1.01 ± 0.17^b	0.61
	7	0.35 ± 0.28	0.56 ± 0.36^a	1.60	1.52 ± 0.13	0.29 ± 0.18^b	0.19
Epithelial thickness (mm)	4	0.09 ± 0.01	0.06 ± 0.01^a	0.67	0.07 ± 0.01	0.10 ± 0.01^b	1.43
	7	0.08 ± 0.01	0.05 ± 0.01^a	0.63	0.06 ± 0.01	0.08 ± 0.01^b	1.33
Epithelial area (mm²)	4	0.21 ± 0.02	0.11 ± 0.02^a	0.52	0.17 ± 0.01	0.23 ± 0.02^b	1.35
	7	0.18 ± 0.01	0.10 ± 0.02^a	0.56	0.10 ± 0.01	0.16 ± 0.01^b	1.60

All numbers are means ± SEM.

Significant change compared to normoglycemic K14.Cre⁻.Foxo1^L/L mice (P < 0.05).

Significant change compared to diabetic K14.Cre⁻.Foxo1^L/L mice (P < 0.05).