Table 2. Quantification of the polarity... | Rockefeller University Press

Table 2.

Quantification of the polarity index of the S1935 mutants

Endogenous MHCII-B depletion	Rescued with	Polarity index ± SD	P-value
No (control)	N/A	2.23 ± 0.81	<0.01^b
Yes	No (MHCII-B knockdown)	1.24 ± 0.19	<0.01^a
Yes	GFP–MHCII-B wild type (rescue)	2.01 ± 0.54	<0.01^b
Yes	GFP–MHCII-B 1935A	2.06 ± 0.65	<0.01^b
Yes	GFP–MHCII-B 1935D	1.35 ± 0.29	<0.01^a
Yes	GFP–MHCII-B ADDDD	1.95 ± 0.73	<0.01^b
Yes	GFP–MHCII-B DAAAA	1.36 ± 0.32	<0.01^a

Endogenous MHCII-B depletion	Rescued with	Polarity index ± SD	P-value
No (control)	N/A	2.23 ± 0.81	<0.01^b
Yes	No (MHCII-B knockdown)	1.24 ± 0.19	<0.01^a
Yes	GFP–MHCII-B wild type (rescue)	2.01 ± 0.54	<0.01^b
Yes	GFP–MHCII-B 1935A	2.06 ± 0.65	<0.01^b
Yes	GFP–MHCII-B 1935D	1.35 ± 0.29	<0.01^a
Yes	GFP–MHCII-B ADDDD	1.95 ± 0.73	<0.01^b
Yes	GFP–MHCII-B DAAAA	1.36 ± 0.32	<0.01^a

Data are the quantification of four experiments (number of cells >200/condition). P-value denotes significance according to the Mann–Whitney test. N/A, not applicable.

Versus MHCII-B–depleted cells rescued with GFP–MHCII-B wild type (row 3).

Versus nonrescued cells (row 2).

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