49 human RNA-binding proteins (containing the Pfam RRM [PF00076] and/or annotated with the GO term for RNA-binding [GO:0003723]) also harbor predicted prion-like domains. Prion score, based on Alberti et al. (2009), indicates the maximum log-likelihood ratio for prion-like amino acid composition vs. non–prion-like amino acid composition in any 60 consecutive amino acid window contained in a region parsed as prion-like by the hidden Markov model. Prion domain rank is from 21,873 human proteins, 250 of which had positive prion score. Localization to P-bodies or SGs is based on literature searches, especially Buchan and Parker (2009). Human disease connections for select proteins are indicated.