Table 1. Phenotypes of new NDC1 alleles... | Rockefeller University Press

Table 1.

Phenotypes of new NDC1 alleles

	Binding by MYTH^a			Growth on 5-FOA^b
Genotype	Pom34	Nbp1	Mps3	POM152	pom152Δ
NDC1	++	++	+	++	++
ndc1-V180G	−	−	−	−	−
ndc1-A290E	++	−/+	−	ts	ts
ndc1-A527E	++	−/+	−	++	ND
ndc1-A298K	++	+	−	−	−
ndc1-L294R	++	−/+	−	−	−
ndc1-E293A	++	+	−	−	−
ndc1-R306D	++	++	−	++	++
ndc1-V340Q	++	++	−	−	−
ndc1-L562S	++	++	−/+	−	++

	Binding by MYTHa			Growth on 5-FOAb
Genotype	Pom34	Nbp1	Mps3	POM152	pom152Δ
NDC1	++	++	+	++	++
ndc1-V180G	−	−	−	−	−
ndc1-A290E	++	−/+	−	ts	ts
ndc1-A527E	++	−/+	−	++	ND
ndc1-A298K	++	+	−	−	−
ndc1-L294R	++	−/+	−	−	−
ndc1-E293A	++	+	−	−	−
ndc1-R306D	++	++	−	++	++
ndc1-V340Q	++	++	−	−	−
ndc1-L562S	++	++	−/+	−	++

ND, not determined.

++, indicates robust binding; +, indicates binding; −/+, indicates weak binding; −, indicates no binding.

++, indicates growth at all temperatures; −, indicates no growth at all temperatures; ts, indicates growth at 23°C but not 37°C.