Table 1.

Analysis of complex assemblies by SLS

Sample MM exp. MM calc. Copy no. 
 kD kD  
Myo4p-C 54.9 ± 1.1 56.7 
She3p/Myo4p-C 160.2 ± 3.6 153.2 2/1 
ASH1-E3-51/She2p 139.2 ± 8.0 147.2 2/4 
ASH1-E3-77-tRNA/She2p 196.3 ± 5.1 211.8 2/4 
IST2-tRNA/She2p 176.6 ± 2.6 202.1 2/4 
ASH1-E3-77-tRNA/She2p/She3p/Myo4p-C 502.8 ± 9.8 518.2 2/4/4/2 
Sample MM exp. MM calc. Copy no. 
 kD kD  
Myo4p-C 54.9 ± 1.1 56.7 
She3p/Myo4p-C 160.2 ± 3.6 153.2 2/1 
ASH1-E3-51/She2p 139.2 ± 8.0 147.2 2/4 
ASH1-E3-77-tRNA/She2p 196.3 ± 5.1 211.8 2/4 
IST2-tRNA/She2p 176.6 ± 2.6 202.1 2/4 
ASH1-E3-77-tRNA/She2p/She3p/Myo4p-C 502.8 ± 9.8 518.2 2/4/4/2 

Molecular masses from experimental SLS analysis (MM exp.) compared with calculated molecular masses (MM calc.) for complexes with the indicated copy number of proteins and RNAs. Data represent the means and standard deviation of at least three experiments with varying sample concentrations. Calculated theoretical molecular masses of the monomers are as follows: 56.7 kD (Myo4-C), 48.2 kD (She3p), 28.7 kD (She2p), 16.3 kD (ASH1-E3-51), 48.7 kD (ASH1-E3-77-tRNA), and 43.7 kD (IST2-tRNA).

or Create an Account

Close Modal
Close Modal