Embryonic lethality of ATM D2899A mice occurs before E9.5
| Founder line | AtmTgD2899AAtm+/+ | Atm+/+ | AtmTgD2899AAtm+/− | Atm+/− | AtmTgD2899AAtm−/− | Atm−/− | Total genotyped | Absorb |
| G1 observed | 3 | 9 | 7 | 13 | 1 | 5 | 38 | 5 |
| G1 expected | 5 | 5 | 10 | 10 | 5 | 5 | ||
| H7 observed | 0 | 5 | 2 | 8 | 0 | 2 | 17 | 2 |
| H7 expected | 2 | 2 | 4 | 4 | 2 | 2 | ||
| D4 observed | 0 | 4 | 0 | 1 | 0 | 0 | 5 | 1 |
| D4 expected | 0.5 | 0.5 | 1 | 1 | 0.5 | 0.5 | ||
| F5 observed | 1 | 4 | 5 | 2 | 0 | 0 | 12 | 3 |
| F5 expected | 1.5 | 1.5 | 3 | 3 | 1.5 | 1.5 | ||
| I2 observed | 4 | 3 | 4 | 6 | 0 | 2 | 19 | 4 |
| I2 expected | 2 | 2 | 5 | 5 | 2 | 2 | ||
| Total E9.5 embryos observed | 11 | 25 | 18 | 30 | 1 | 9 | 91 | 15 |
| Total E9.5 embryos expected | 11 | 11 | 23 | 23 | 11 | 11 |
| Founder line | AtmTgD2899AAtm+/+ | Atm+/+ | AtmTgD2899AAtm+/− | Atm+/− | AtmTgD2899AAtm−/− | Atm−/− | Total genotyped | Absorb |
| G1 observed | 3 | 9 | 7 | 13 | 1 | 5 | 38 | 5 |
| G1 expected | 5 | 5 | 10 | 10 | 5 | 5 | ||
| H7 observed | 0 | 5 | 2 | 8 | 0 | 2 | 17 | 2 |
| H7 expected | 2 | 2 | 4 | 4 | 2 | 2 | ||
| D4 observed | 0 | 4 | 0 | 1 | 0 | 0 | 5 | 1 |
| D4 expected | 0.5 | 0.5 | 1 | 1 | 0.5 | 0.5 | ||
| F5 observed | 1 | 4 | 5 | 2 | 0 | 0 | 12 | 3 |
| F5 expected | 1.5 | 1.5 | 3 | 3 | 1.5 | 1.5 | ||
| I2 observed | 4 | 3 | 4 | 6 | 0 | 2 | 19 | 4 |
| I2 expected | 2 | 2 | 5 | 5 | 2 | 2 | ||
| Total E9.5 embryos observed | 11 | 25 | 18 | 30 | 1 | 9 | 91 | 15 |
| Total E9.5 embryos expected | 11 | 11 | 23 | 23 | 11 | 11 |
Shown are the expected and observed genotypes from breeding AtmTgD2899AAtm+/− with Atm+/− mice. Note the comparison between the total number of ATM kinase-inactive and Atm-null embryos.