Quantification of neuron positioning defects in genetic chimeras composed of wild-type and cxcr7b−/− embryos
| Genotype | Position relative to MHB | n (neurons) | Ectopic | ||
| Anterior (ectopic) | Adjacent (ectopic) | Posterior (correct) | |||
| % | |||||
| Wild type into TgSN-less wild type | 0 | 11 | 154 | 165 | 6.70 |
| Wild-type into TgSN-less cxcr7b−/− | 94 | 81 | 20 | 195 | 89.70 |
| cxcr7b−/− into TgSN-less wild type | 7 | 48 | 328 | 383 | 14.40 |
| cxcr7b−/− into TgSN-less cxcr7b−/− | 55 | 50 | 16 | 121 | 86.80 |
| Genotype | Position relative to MHB | Ectopic | |||
| Anterior (ectopic) | Adjacent (ectopic) | Posterior (correct) | |||
| Wild type into TgSN-less wild type | 0 | 11 | 154 | 165 | 6.70 |
| Wild-type into TgSN-less | 94 | 81 | 20 | 195 | 89.70 |
| 7 | 48 | 328 | 383 | 14.40 | |
| 55 | 50 | 16 | 121 | 86.80 | |
Neurons were categorized according to their position with respect to the MHB at the 12-somite stage as diagrammed in Fig. 5 U.
Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.