Table 3.

Quantification of neuron positioning defects in genetic chimeras composed of wild-type and cxcr7b−/− embryos

Genotype Position relative to MHB n (neurons) Ectopic 
 Anterior (ectopic) Adjacent (ectopic) Posterior (correct)   
     % 
Wild type into TgSN-less wild type 11 154 165 6.70 
Wild-type into TgSN-less cxcr7b−/− 94 81 20 195 89.70 
cxcr7b−/− into TgSN-less wild type 48 328 383 14.40 
cxcr7b−/− into TgSN-less cxcr7b−/− 55 50 16 121 86.80 
Genotype Position relative to MHB n (neurons) Ectopic 
 Anterior (ectopic) Adjacent (ectopic) Posterior (correct)   
     % 
Wild type into TgSN-less wild type 11 154 165 6.70 
Wild-type into TgSN-less cxcr7b−/− 94 81 20 195 89.70 
cxcr7b−/− into TgSN-less wild type 48 328 383 14.40 
cxcr7b−/− into TgSN-less cxcr7b−/− 55 50 16 121 86.80 

Neurons were categorized according to their position with respect to the MHB at the 12-somite stage as diagrammed in Fig. 5 U.

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