Table 2. Quantification of neuron... | Rockefeller University Press

Table 2.

Quantification of neuron positioning defects in different chemokine signaling mutants

Genotype	Position relative to MHB			n
	Anterior	Adjacent	Posterior	Neurons	Embryos
Wild type	1	10	767	778	20
mean	0.05	0.5	38.35
SD	0.22	0.69	2.28
SEM	0.05	0.15	0.51
*cxcr7b^−/−*	461	773	787	2,021	39
mean	11.82	19.82	20.18
SD	5.93	6	5.47
SEM	0.95	0.96	0.88
*cxcr4b^−/−*	541	586	205	1,332	27
mean	20.04	21.7	7.59
SD	6.83	9.08	5.39
SEM	1.31	1.75	1.04
**cxcr7b^−/−; cxcr4b^−/−**	1,211	777	177	2,165	39
mean	31.05	19.92	4.54
SD	10.29	5.8	4.78
SEM	1.65	0.93	0.77
SDF1a^−/−; SDF1b-MO	500	502	106	1,108	22
mean	22.73	22.82	4.82
SD	8.21	6.43	3.95
SEM	1.75	1.37	0.84

Genotype	Position relative to MHB			n
	Anterior	Adjacent	Posterior	Neurons	Embryos
Wild type	1	10	767	778	20
mean	0.05	0.5	38.35
SD	0.22	0.69	2.28
SEM	0.05	0.15	0.51
*cxcr7b^−/−*	461	773	787	2,021	39
mean	11.82	19.82	20.18
SD	5.93	6	5.47
SEM	0.95	0.96	0.88
*cxcr4b^−/−*	541	586	205	1,332	27
mean	20.04	21.7	7.59
SD	6.83	9.08	5.39
SEM	1.31	1.75	1.04
**cxcr7b^−/−; cxcr4b^−/−**	1,211	777	177	2,165	39
mean	31.05	19.92	4.54
SD	10.29	5.8	4.78
SEM	1.65	0.93	0.77
SDF1a^−/−; SDF1b-MO	500	502	106	1,108	22
mean	22.73	22.82	4.82
SD	8.21	6.43	3.95
SEM	1.75	1.37	0.84

Neurons were categorized according to their position with respect to the MHB at the 12-somite stage as diagrammed in Fig. 5 U.