Table 1. Dl colocalization with Sara,... | Rockefeller University Press

Table 1.

Dl colocalization with Sara, Hrs, and Rab11

Dl variant	Sara			Hrs			Rab11
	Colocalization	n	P-value	Colocalization	n	P-value	Colocalization	n	P-value
	%			%			%
Alone
wt	46	166	−	37	109	−	15	141	−
Dli1	60	106	0.02	37	73	1.00	14	200	0.75
Dli2	54	112	0.22	33	122	0.58	13	238	0.54
Dli1/2	47	100	0.90	18^a	201	<0.01^a	14	125	1.00
DlΔC	42	114	0.62	18^a	104	<0.01^a	16	129	1.00
Dl-LDL	19^a	503	<0.01^a	34	131	0.68	14	151	0.87
+Neur
wt	45	317	0.92^b	5^a	222	<0.01^a^b	10	192	0.24^b
Dli1	49	214	0.48	6	143	0.63	11	150	1.00
Dli2	46	226	0.86	6	343	0.57	11	240	1.00
Dli1/2	34	170	0.02	4	93	1.00	11	124	1.00
DlΔC	46	156	0.85	5	134	0.80	10	129	1.00
+Mib1
wt	50	92	0.52^b	NT	−	−	13	286	0.66^b

Dl variant	Sara			Hrs			Rab11
	Colocalization	n	P-value	Colocalization	n	P-value	Colocalization	n	P-value
	%			%			%
Alone
wt	46	166	−	37	109	−	15	141	−
Dli1	60	106	0.02	37	73	1.00	14	200	0.75
Dli2	54	112	0.22	33	122	0.58	13	238	0.54
Dli1/2	47	100	0.90	18^a	201	<0.01^a	14	125	1.00
DlΔC	42	114	0.62	18^a	104	<0.01^a	16	129	1.00
Dl-LDL	19^a	503	<0.01^a	34	131	0.68	14	151	0.87
+Neur
wt	45	317	0.92^b	5^a	222	<0.01^a^b	10	192	0.24^b
Dli1	49	214	0.48	6	143	0.63	11	150	1.00
Dli2	46	226	0.86	6	343	0.57	11	240	1.00
Dli1/2	34	170	0.02	4	93	1.00	11	124	1.00
DlΔC	46	156	0.85	5	134	0.80	10	129	1.00
+Mib1
wt	50	92	0.52^b	NT	−	−	13	286	0.66^b

The percentage of colocalization of each Dl variant with Sara, Hrs, and Rab11 is shown. The numbers refer to the percentage of Dl puncta that are also positive for each endocytic marker. n = total number of Dl puncta scored. P-values were calculated using the Fisher exact test against the Dl wt control. In the +Neur and +Mib1 sections, Dl variants were coexpressed with UAS-Neur or UAS-YFP-Mib1, respectively. The variant +Neur p-values are computed against Dl wt +Neur. Minus signs indicate not applicable data. NT, not tested.

Values below 0.01 are considered significantly different than wt.

The wt +Neur/Mib1 colocalization p-values are computed against Dl wt alone.

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