Table 1.

Kinetic constants of the interaction of Drg1 and Drg1EQ1 with immobilized Rlp24C (two-state reaction)

Protein Nucleotide kon1 koff1 kon2 koff2 
  M−1 s−1 s−1 s−1 s−1 
Drg1 ATP 5.4 ± 0.9 × 104 1.3 ± 0.1 × 10−1 2.8 ± 0.5 × 10−2 2.5 ± 0.5 × 10−3 
Drg1 AMP-PNP 1.1 ± 0.1 × 105 6.0 ± 0.9 × 10−2 1.5 ± 0.2 × 10−2 6.9 ± 0.5 × 10−4 
Drg1EQ1 ATP 5.8 ± 0.4 × 104 5.1 ± 1.5 × 10−3 7.2 ± 1.2 × 10−3 9.8 ± 0.2 × 10−14 
Drg1EQ1 AMP-PNP 5.4 ± 0.7 × 104 3.5 ± 1.1 × 10−3 1.1 ± 0.2 × 10−2 8.4 ± 7.4 × 10−14 
Protein Nucleotide kon1 koff1 kon2 koff2 
  M−1 s−1 s−1 s−1 s−1 
Drg1 ATP 5.4 ± 0.9 × 104 1.3 ± 0.1 × 10−1 2.8 ± 0.5 × 10−2 2.5 ± 0.5 × 10−3 
Drg1 AMP-PNP 1.1 ± 0.1 × 105 6.0 ± 0.9 × 10−2 1.5 ± 0.2 × 10−2 6.9 ± 0.5 × 10−4 
Drg1EQ1 ATP 5.8 ± 0.4 × 104 5.1 ± 1.5 × 10−3 7.2 ± 1.2 × 10−3 9.8 ± 0.2 × 10−14 
Drg1EQ1 AMP-PNP 5.4 ± 0.7 × 104 3.5 ± 1.1 × 10−3 1.1 ± 0.2 × 10−2 8.4 ± 7.4 × 10−14 

Mean values determined from five independent injections over at least three different CM5-chips.

or Create an Account

Close Modal
Close Modal