Table 1. DA-7 miRNA-regulated genes and... | Rockefeller University Press

Table 1.

DA-7 miRNA-regulated genes and miR targets

miRNA	Down-regulated genes		Up-regulated genes		miR targets
	n	Mean ± SD	n	Mean ± SD	n	Cons.	Not Cons.
miR-1	2,922	−0.49 ± 0.29	3,326	0.46 ± 0.28	476	184	292
miR-34a	2,063	−0.39 ± 0.20	2,136	0.40 ± 0.21	407	108	299
miR-365	2,569	−0.46 ± 0.27	3,142	0.40 ± 0.21	384	66	318
miR-22	2,136	−0.37 ± 0.18	2,827	0.41 ± 0.22	338	75	263
miR-29a	1,725	−0.40 ± 0.20	2,188	0.37 ± 0.18	413	234	179
miR-145	1,430	−0.39 ± 0.21	2,064	0.39 ± 0.30	293	83	210
let-7b	1,991	−0.39 ± 0.19	2,022	0.40 ± 0.22	355	199	156

miRNA	Down-regulated genes		Up-regulated genes		miR targets
	n	Mean ± SD	n	Mean ± SD	n	Cons.	Not Cons.
miR-1	2,922	−0.49 ± 0.29	3,326	0.46 ± 0.28	476	184	292
miR-34a	2,063	−0.39 ± 0.20	2,136	0.40 ± 0.21	407	108	299
miR-365	2,569	−0.46 ± 0.27	3,142	0.40 ± 0.21	384	66	318
miR-22	2,136	−0.37 ± 0.18	2,827	0.41 ± 0.22	338	75	263
miR-29a	1,725	−0.40 ± 0.20	2,188	0.37 ± 0.18	413	234	179
miR-145	1,430	−0.39 ± 0.21	2,064	0.39 ± 0.30	293	83	210
let-7b	1,991	−0.39 ± 0.19	2,022	0.40 ± 0.22	355	199	156

The effect of DA-7 miRNAs on gene expression in proliferating myoblasts (C2C12) in three independent experiments (see Materials and methods for details) is summarized. The number (n) of genes classified as miR targets among all the genes down-regulated by each miRNA, classified as “Conserved” (Cons.) or “Not Conserved” (Not Cons.) according to TargetScan 5.1 are also shown.

View Large

This Feature Is Available To Subscribers Only