Table III.

Kinetic parameters of microtubule polymerization dynamics in the EBN-Sentin-GFP rescue experiment

Parameters Control EB1–Sentin RNAi 
  GFP not expressed GFP expressed 
Growth rate (µm/min) 4.5 ± 0.7 4.1 ± 0.4 4.3 ± 0.9 
 4.6 ± 1.7m 4.0 ± 1.7m 4.3 ± 1.6m 
Shrink rate (µm/min) 10.6 ± 2.3 9.6 ± 3.4 8.4 ± 0.9 
 10.9 ± 5.3m 9.9 ± 5.9m 8.4 ± 3.3m 
Catastrophe frequency (s−10.012 ± 0.004 0.006 ± 0.004 0.016 ± 0.004 
Rescue frequency (s−10.005 ± 0.002 0.002 ± 0.002 0.010 ± 0.005 
Time in growth (%) 39.3 ± 12.1 11.5 ± 7.6 36.4 ± 7.9 
Time in shrink (%) 14.1 ± 4.4 5.4 ± 4.3 16.8 ± 5.3 
Time in pause (%) 46.6 ± 13.2 83.1 ± 11.1 46.8 ± 11.8 
Parameters Control EB1–Sentin RNAi 
  GFP not expressed GFP expressed 
Growth rate (µm/min) 4.5 ± 0.7 4.1 ± 0.4 4.3 ± 0.9 
 4.6 ± 1.7m 4.0 ± 1.7m 4.3 ± 1.6m 
Shrink rate (µm/min) 10.6 ± 2.3 9.6 ± 3.4 8.4 ± 0.9 
 10.9 ± 5.3m 9.9 ± 5.9m 8.4 ± 3.3m 
Catastrophe frequency (s−10.012 ± 0.004 0.006 ± 0.004 0.016 ± 0.004 
Rescue frequency (s−10.005 ± 0.002 0.002 ± 0.002 0.010 ± 0.005 
Time in growth (%) 39.3 ± 12.1 11.5 ± 7.6 36.4 ± 7.9 
Time in shrink (%) 14.1 ± 4.4 5.4 ± 4.3 16.8 ± 5.3 
Time in pause (%) 46.6 ± 13.2 83.1 ± 11.1 46.8 ± 11.8 

Means ± SD. SD represents either microtubule to-microtubule (marked with an m) or cell to cell (others) variability (80 microtubules and 5 cells).

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