Table III.

Parameters of ER-NE protein dynamics estimated using modeling-based analysis

NET t1/2 D in ER D in NE ONM/INM ratio t1/2, INM binding t1/2, NPC translocation 
  μm2/s μm2/s   s 
NET55 14.9 0.01–0.03 0.05–0.07 45:55 90–110 s 50–70 
LAP2 25 0.05–0.1 0.05–0.1 30:70 8–12 min 60–80 
LAP1L 233 0.05–0.07 0.08–0.1 05:95a 9–14 min 70–140 
NET t1/2 D in ER D in NE ONM/INM ratio t1/2, INM binding t1/2, NPC translocation 
  μm2/s μm2/s   s 
NET55 14.9 0.01–0.03 0.05–0.07 45:55 90–110 s 50–70 
LAP2 25 0.05–0.1 0.05–0.1 30:70 8–12 min 60–80 
LAP1L 233 0.05–0.07 0.08–0.1 05:95a 9–14 min 70–140 
a

Inferred from the model, all others were calculated.

or Create an Account

Close Modal
Close Modal