Table 1.

Offspring from TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1+/− and TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1−/− mouse intercrosses

Crosses Total pups Genotype Pups (expected), p-value 
TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1+/− 131 TRF1flox/flox K5-Cre+/T 53BP1+/− and TRF1flox/flox K5-Cre+/T 53BP1−/− 12 (16), P = 0.4 and 14 (16), P = 0.85 
TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1−/− 67 TRF1flox/flox K5-Cre+/T 53BP1−/− and TRF1flox/flox 53BP1−/− 10 (17), P = 0.2 and14 (17), P = 0.7 
Crosses Total pups Genotype Pups (expected), p-value 
TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1+/− 131 TRF1flox/flox K5-Cre+/T 53BP1+/− and TRF1flox/flox K5-Cre+/T 53BP1−/− 12 (16), P = 0.4 and 14 (16), P = 0.85 
TRF1flox/flox 53BP1−/− and TRF1flox/+ K5-Cre+/T 53BP1−/− 67 TRF1flox/flox K5-Cre+/T 53BP1−/− and TRF1flox/flox 53BP1−/− 10 (17), P = 0.2 and14 (17), P = 0.7 
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