Table 1.

Categories of genes changed twofold or more upon Rnq1 overexpression

Gene expression GO term Cluster frequency Background frequency P-value Genes 
Up after 6 h Protein folding 3/8; 37.5% 88/7,167; 1.2% 0.00201 HSP104, SIS1, and SSA4 
Up after 8 h Protein folding 4/23; 17.4% 88/7,167; 1.2% 0.01368 HSP26, HSP104, SIS1, and SSA4 
Down after 6 h Cytokinesis, completion of separation 4/13; 30.8% 11/7,167; 0.2% 4.90 × 10−8 CTS1, DSE2, DSE4, and SCW11 
Down after 8 h Cytokinesis, completion of separation 5/27; 18.5% 11/7,167; 0.2% 1.98 × 10−8 CTS1, DSE1, DSE2, DSE4, and SCW11 
Down after 8 h Hexose transport 3/27; 11.1% 24/7,167; 0.3% 0.00778 HXT3, HXT6, and HXT7 
Gene expression GO term Cluster frequency Background frequency P-value Genes 
Up after 6 h Protein folding 3/8; 37.5% 88/7,167; 1.2% 0.00201 HSP104, SIS1, and SSA4 
Up after 8 h Protein folding 4/23; 17.4% 88/7,167; 1.2% 0.01368 HSP26, HSP104, SIS1, and SSA4 
Down after 6 h Cytokinesis, completion of separation 4/13; 30.8% 11/7,167; 0.2% 4.90 × 10−8 CTS1, DSE2, DSE4, and SCW11 
Down after 8 h Cytokinesis, completion of separation 5/27; 18.5% 11/7,167; 0.2% 1.98 × 10−8 CTS1, DSE1, DSE2, DSE4, and SCW11 
Down after 8 h Hexose transport 3/27; 11.1% 24/7,167; 0.3% 0.00778 HXT3, HXT6, and HXT7 

Genes that changed more than twofold in the [RNQ+] strain in comparison with the [rnq] strain were analyzed for gene ontology (GO) term enrichment.

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