Table I.

Germline transmission of CLIP and CLIPm transgenes

Founders Germline transmission Expression (E5.5) Expression in adult tissue 
CLIP (12) 10/12 6/9 3/8 
CLIPm (9) 6/7 4/5 2/5 
Total (21) 16/19 (84%) 10/14 (71%) 5/13 (38%) 
Founders Germline transmission Expression (E5.5) Expression in adult tissue 
CLIP (12) 10/12 6/9 3/8 
CLIPm (9) 6/7 4/5 2/5 
Total (21) 16/19 (84%) 10/14 (71%) 5/13 (38%) 

Transgenic lines positive for germline transmission were tested for transgene expression at E5.5 and in adult tissues. Expression was considered positive when detectable by an epifluorescent M205FA stereomicroscope. Because of premature loss, three lines could not be analyzed.

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