Germline transmission of CLIP and CLIPm transgenes
Founders
Germline transmission
Expression (E5.5)
Expression in adult tissue
CLIP (12)
10/12
6/9
3/8
CLIPm (9)
6/7
4/5
2/5
Total (21)
16/19 (84%)
10/14 (71%)
5/13 (38%)
Founders
Germline transmission
Expression (E5.5)
Expression in adult tissue
CLIP (12)
10/12
6/9
3/8
CLIPm (9)
6/7
4/5
2/5
Total (21)
16/19 (84%)
10/14 (71%)
5/13 (38%)
Transgenic lines positive for germline transmission were tested for transgene expression at E5.5 and in adult tissues. Expression was considered positive when detectable by an epifluorescent M205FA stereomicroscope. Because of premature loss, three lines could not be analyzed.