Table I.

Effect of Set7 and the Set7-dn mutant on myoblast proliferation and differentiation

Treatment Growth medium Differentiation medium at 24 h Differentiation medium at 48 h 
 Phospho-H3–positive cells Phospho-H3–positive cells Myogenin-positive cells Myogenin-positive cells MHC-positive cells 
 Total number Relative to control Total number Relative to control Total number Relative to control Total number Relative to control Total number Relative to control 
  %  %  %  %  % 
pcDNA 94 100.0 59 100.0 197 100.0 363 100.0 120 100.0 
Set7 92 97.9 62 105.1 193 98.0 370 101.9 113 94.2 
Set7-dn 135 143.6 95 161.0 142 72.1 309 85.1 81 67.5 
Treatment Growth medium Differentiation medium at 24 h Differentiation medium at 48 h 
 Phospho-H3–positive cells Phospho-H3–positive cells Myogenin-positive cells Myogenin-positive cells MHC-positive cells 
 Total number Relative to control Total number Relative to control Total number Relative to control Total number Relative to control Total number Relative to control 
  %  %  %  %  % 
pcDNA 94 100.0 59 100.0 197 100.0 363 100.0 120 100.0 
Set7 92 97.9 62 105.1 193 98.0 370 101.9 113 94.2 
Set7-dn 135 143.6 95 161.0 142 72.1 309 85.1 81 67.5 
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