Table II. CK2-mediated regulation of... | Rockefeller University Press

Table II.

CK2-mediated regulation of occludin, claudin-1, claudin-2, and ZO-1 mobile fractions

Condition	Occludin	Claudin-1	Claudin-2	ZO-1
Steady state	68 ± 3	36 ± 2	33 ± 3	48 ± 3
CK2 inhibition	52 ± 5^a^b		51 ± 5^a	60 ± 4^a
Occludin knockdown/occludin S408A	49 ± 3^a	57 ± 3^a	51 ± 2^a	61 ± 4^a
Occludin knockdown/CK2 inhibition			27 ± 1	45 ± 4
ZO-1 knockdown/CK2 inhibition			32 ± 2

Condition	Occludin	Claudin-1	Claudin-2	ZO-1
Steady state	68 ± 3	36 ± 2	33 ± 3	48 ± 3
CK2 inhibition	52 ± 5ab		51 ± 5a	60 ± 4a
Occludin knockdown/occludin S408A	49 ± 3a	57 ± 3a	51 ± 2a	61 ± 4a
Occludin knockdown/CK2 inhibition			27 ± 1	45 ± 4
ZO-1 knockdown/CK2 inhibition			32 ± 2

Data changes are significant (P < 0.05) relative to steady state.

Data were confirmed by in vitro CK2 knockdown and in vivo CK2 inhibition.