Targeted integration frequencies
| Genotype | OVALBMIN locus | POLK locus |
| Wild type | 18/19 (95%) | 2/23 (8.7%) |
| POLQ−/− | 20/21 (95%) | ND |
| POLN−/− | 22/23 (96%) | 8/51 (16%) |
| POLN−/−/POLQ−/− | 29/31 (94%) | 1/10 (10%) |
| Genotype | OVALBMIN locus | POLK locus |
| Wild type | 18/19 (95%) | 2/23 (8.7%) |
| POLQ−/− | 20/21 (95%) | ND |
| POLN−/− | 22/23 (96%) | 8/51 (16%) |
| POLN−/−/POLQ−/− | 29/31 (94%) | 1/10 (10%) |
Wild-type and knockout cells were transfected with targeting constructs of the indicated genotype. The number of targeted clones/number of drug-resistant clones analyzed is shown.