Table I.

Fold changes of genes involved in oxidative stress responses

GeneFold change
References

In Oct1−/− a
In Lmnb1Δ/Δb

Peroxiredoxin 2 (Prdx210.2 0.8 Sanchez-Font et al., 2003 c 
Serine (or cysteine) proteinase inhibitor, clade G,     member 1 (Serping14.7 −1.5 Tantin et al., 2005  
RAD52 motif 1 (Rdm13.6 −1.05 Tantin et al., 2005  
Glutathione peroxidase 1 (GPx10.2 0.4 Fu et al., 2001 c 
Glutathione peroxidase 3 (Gpx32.6 −1.65 Ouyang et al., 2005  
Tissue inhibitor of metalloproteinase 3 (Timp32.53 −0.72 Winokur et al., 2003 c 
Interleukin 6 (Il-62.48 −3.8 Orosz et al., 2007  
Growth arrest specific 6 (Gas62.04 −0.50 Valverde, 2005  
Growth arrest specific 5 (Gas5−3.52 0.01 Tantin et al., 2005  
Superoxide dismutase 1, soluble (Sod1−0.4 Ali et al., 2006 c 
Selenoprotein P, plasma, 1 (Sepp1−1.13 Steinbrenner et al., 2006 c 
GST, mu 1 (Gstm1−0.6 Aydemir et al., 2007 c 
GST, mu 2 (Gstm2−2 Tantin et al., 2005  
Microsomal GST (Mgst0.5 −4 Hayes and Strange, 2000  
Glutamate cysteine ligase (γ-glutamyl-cysteine synthetase),     regulatory (Glclr0.3 −0.4 Rozet et al., 1998  
GeneFold change
References

In Oct1−/− a
In Lmnb1Δ/Δb

Peroxiredoxin 2 (Prdx210.2 0.8 Sanchez-Font et al., 2003 c 
Serine (or cysteine) proteinase inhibitor, clade G,     member 1 (Serping14.7 −1.5 Tantin et al., 2005  
RAD52 motif 1 (Rdm13.6 −1.05 Tantin et al., 2005  
Glutathione peroxidase 1 (GPx10.2 0.4 Fu et al., 2001 c 
Glutathione peroxidase 3 (Gpx32.6 −1.65 Ouyang et al., 2005  
Tissue inhibitor of metalloproteinase 3 (Timp32.53 −0.72 Winokur et al., 2003 c 
Interleukin 6 (Il-62.48 −3.8 Orosz et al., 2007  
Growth arrest specific 6 (Gas62.04 −0.50 Valverde, 2005  
Growth arrest specific 5 (Gas5−3.52 0.01 Tantin et al., 2005  
Superoxide dismutase 1, soluble (Sod1−0.4 Ali et al., 2006 c 
Selenoprotein P, plasma, 1 (Sepp1−1.13 Steinbrenner et al., 2006 c 
GST, mu 1 (Gstm1−0.6 Aydemir et al., 2007 c 
GST, mu 2 (Gstm2−2 Tantin et al., 2005  
Microsomal GST (Mgst0.5 −4 Hayes and Strange, 2000  
Glutamate cysteine ligase (γ-glutamyl-cysteine synthetase),     regulatory (Glclr0.3 −0.4 Rozet et al., 1998  

Log fold changes with P < 0.05 are shown.

a

Data from Tantin et al., 2005.

b

Log2 fold ratios.

c

Reports of down-regulation being associated with increased susceptibility to ROS.

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