Table II.

Summary of telomere localization mutants

MutantORF nameRap1 phenotype
% zone 1 (n,a p-valueb)


Type
Score
G1
S
Controls      
    WT    66.0 (295, 1.00) 67.5 (336, 1.00) 
    sir4Δ YDR227W B 3 46.0 (124, 1.5 × 10−5) 58.2 (91, 0.01) 
    yku70Δ YMR284W B 3 54.4 (184, 1.5 × 10−4) 55.7 (87, 2.5 × 10−5) 
G1 and S      
    ctf18Δ YMR078C B 3 40.2 (247, 5.3 × 10−12) 51.9 (212, 0.002) 
    pgd1Δ YGL025C B 3 37.9 (112, 3.5 × 10−11) 44.8 (95, 6.2 × 10−7) 
    rrm3Δ YHR031C B 3 45.2 (62, 0.002) 38.4 (86, 2.0 × 10−8) 
G1 specific      
    elp4Δ YPL101W B/C 2 45.7 (35, 0.01) 71.9 (32, 0.68) 
    tel1Δ YBL088C B 2 48.1 (54, 0.002) 63.0 (46, 0.80) 
S specific      
    asf1Δ YJL115W B 3 67.4 (46, 0.05) 43.1 (51, 4.7 × 10−4) 
    mre11Δ YMR224C B 2 59.4 (32, 0.66) 47.3 (55, 5.9 × 10−4) 
    sic1Δ YLR079W A/B 2 74.2 (31, 0.49) 50.0 (42, 0.002) 
Marginal      
    csm4Δ YPL200W B 2 56.8 (37, 0.31) 59.0 (39, 0.26) 
    jjj1Δ YNL227C A/C 2 52.3 (65, 0.03) 57.6 (39, 0.26) 
    sir3Δ YLR442C B 3 56.5 (46, 0.31) 54.5 (44, 0.07) 

Localization of telomere XIV-L in each strain was measured as described in Materials and methods.

a

Total number of cells scored in each cell cycle phase.

b

Calculated by χ2 test against WT value.

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