Table I.

Duration of control mitosis versus MUG

Treatment
Control
MUG
Untreateda 0.7 ± 0.1 (n = 47) 1.6 ± 1.1 (n = 43) 
5 μM nocodazoleb 24.3 ± 9.1 (n = 31) 10.1 ± 5.6 (n = 34) 
200 μM monastrolb 15.8 ± 5.9 (n = 35) 4.5 ± 2.5 (n = 35) 
200 μM monastrol + 100 nM hesperadinb ND 1.8 ± 1.6 (n = 34) 
500 nM taxolb 20.5 ± 5.3 (n = 50) 4.6 ± 3.9 (n = 43) 
500 nM taxol + 100 nM hesperadinb ND 2.6 ± 1.2 (n = 32) 
Treatment
Control
MUG
Untreateda 0.7 ± 0.1 (n = 47) 1.6 ± 1.1 (n = 43) 
5 μM nocodazoleb 24.3 ± 9.1 (n = 31) 10.1 ± 5.6 (n = 34) 
200 μM monastrolb 15.8 ± 5.9 (n = 35) 4.5 ± 2.5 (n = 35) 
200 μM monastrol + 100 nM hesperadinb ND 1.8 ± 1.6 (n = 34) 
500 nM taxolb 20.5 ± 5.3 (n = 50) 4.6 ± 3.9 (n = 43) 
500 nM taxol + 100 nM hesperadinb ND 2.6 ± 1.2 (n = 32) 

Time is given in hours. Error is reported as SD.

a

Defined as nuclear envelope breakdown to maximum furrow ingression.

b

Defined as nuclear envelope breakdown to first cortical telophase activity (blebbing, furrowing, etc.).

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