Table I.

Composition of dynein tail–decorated kinetochores

Protein
(−) Nocodazole
(+) Nocodazole
Dynein motor − − 
p150Glued ++ 
CLIP170 
CLASP1 ++ 
LIS1 ND 
NudE ND 
ZW10 ND 
Hec1 
Aurora B 
Kif2b − 
MCAK a 
Protein
(−) Nocodazole
(+) Nocodazole
Dynein motor − − 
p150Glued ++ 
CLIP170 
CLASP1 ++ 
LIS1 ND 
NudE ND 
ZW10 ND 
Hec1 
Aurora B 
Kif2b − 
MCAK a 

A summary of results on the localization of kinetochore proteins in the presence of dynein tail. (−) Nocodazole data refer only to aligned kinetochores.

a

Despite reported kinetochore localization, we observe most MCAK at spindle poles in control and tail-expressing late prometaphase/metaphase cells.

or Create an Account

Close Modal
Close Modal