Table 3. Calculated surface... | Rockefeller University Press

Table 3.

Calculated surface complementarity and molecular distance between BCMA V3 and APRIL/BAFF

Site in BCMA	Surface complementarity to hAPRIL		Distance to hAPRIL		Surface complementarity to hBAFF		Distance to hBAFF
Site in BCMA	WT	Single mutant	WT	Single mutant	WT	Single mutant	WT	Single mutant
S16G	0.65	0.51	N/A	N/A	0.76	0.76	3.2 Å (to Leu72)	3.2 Å (to Leu72)
H19Y	0.88	0.21	3.8 Å (to Arg81)	2.1 Å (to Arg81)	0.88	0.2	3.7 Å (to Arg92)	2.0 Å (to Arg92)
T36A	0.00	0.00	N/A	N/A	N/A	N/A	N/A	N/A

Site in BCMA	Surface complementarity to hAPRIL		Distance to hAPRIL		Surface complementarity to hBAFF		Distance to hBAFF
Site in BCMA	WT	Single mutant	WT	Single mutant	WT	Single mutant	WT	Single mutant
S16G	0.65	0.51	N/A	N/A	0.76	0.76	3.2 Å (to Leu72)	3.2 Å (to Leu72)
H19Y	0.88	0.21	3.8 Å (to Arg81)	2.1 Å (to Arg81)	0.88	0.2	3.7 Å (to Arg92)	2.0 Å (to Arg92)
T36A	0.00	0.00	N/A	N/A	N/A	N/A	N/A	N/A

N/A, not applicable.