Table 2.

Parameters for [Ca2+]cyt-dependent Ca2+ release activities of CPVT and artificial mutants

ParameterAmaxKACa (mM)KICa (mM)
Mock 0   
WT 0.1248 1.62 × 10–2 3.002 
V2321M 0.1847 1.10 × 10–2 4.847 
R2474S 0.2175 7.03 × 10–3 11.31 
D3638A 0.1214 1.10 × 10–2 2.058 
Q4201R 0.1473 1.04 × 10–2 4.454 
K4392R 0.1324 1.80 × 10–2 2.759 
R4497C 0.1779 1.29 × 10–2 5.553 
K4751Q 0.2733 7.65 × 10–3 1,000 
H4762P 0.09848 2.94 × 10–3 19.5 
K4805R 0.2857 7.35 × 10–3 159.5 
I4867M 0.08865 8.96 × 10–3 1.832 
T4754A 0.1245 2.03 × 10–2 2.178 
I4755A 0.06616 8.18 × 10–3 1.829 
L4756A 0.1925 2.22 × 10–3 741.6 
S4757A 0.1684 1.38 × 10–2 6.967 
S4758A 0.05471 1.95 × 10–2 3.245 
T4754I 0.2953 8.40 × 10–3 17.13 
[ViewLarge]
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal

Gift article access

As a benefit of your subscription, you can share temporary access to restricted articles.

Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.

Please sign in to your personal account to gift article access.

Register

Gift article access

As a benefit of your subscription, you can share temporary access to restricted articles.

Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.

Gift articles remaining: --

Gift article access

Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.

Gift articles remaining: --

Gift article access

As a benefit of your subscription, you can share temporary access to restricted articles.

Each link will stop working after 30 days or 10 uses.

You have reached the limit of 10 links within a 30 day period.

Sharing Unavailable

Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.