Table 3.

Heart-rate variability parameters in conscious sham and TAC mice during the daytime

ParameterSham (n = 7)HF (n = 5)
BasalANS inhibitionBasalANS inhibition
Time domain parameters 
SDNN (ms) 8.83 ± 2.51 2 ± 0.66b 6.89 ± 2.64 3.9 ± 2.55 
RMSSD (ms) 5.03 ± 1.69 2.4 ± 0.89b 3.38 ± 2.21 3.95 ± 2.97 
pNN5 (%) 22.5 ± 13.76 0.35 ± 0.47b 3.52 ± 2.68a 1.49 ± 2.79 
Frequency parameters 
VLFreq/total (nu) 58.5 ± 2.64 48.2 ± 16.13 64.6 ± 4.25 37.9 ± 5.36b 
LFreq normalization (nu) 66.2 ± 11.37 27.4 ± 13.76b 76.3 ± 5.59 53.4 ± 25.04b,a 
HFreq normalization (nu) 33.8 ± 11.37 72.6 ± 13.76b 23.7 ± 5.59 46.6 ± 25.04b,a 
LFreq/HFreq (nu) 2.79 ± 1.13 0.43 ± 0.29b 3.61 ± 1.18 0.82 ± 0.47 
ParameterSham (n = 7)HF (n = 5)
BasalANS inhibitionBasalANS inhibition
Time domain parameters 
SDNN (ms) 8.83 ± 2.51 2 ± 0.66b 6.89 ± 2.64 3.9 ± 2.55 
RMSSD (ms) 5.03 ± 1.69 2.4 ± 0.89b 3.38 ± 2.21 3.95 ± 2.97 
pNN5 (%) 22.5 ± 13.76 0.35 ± 0.47b 3.52 ± 2.68a 1.49 ± 2.79 
Frequency parameters 
VLFreq/total (nu) 58.5 ± 2.64 48.2 ± 16.13 64.6 ± 4.25 37.9 ± 5.36b 
LFreq normalization (nu) 66.2 ± 11.37 27.4 ± 13.76b 76.3 ± 5.59 53.4 ± 25.04b,a 
HFreq normalization (nu) 33.8 ± 11.37 72.6 ± 13.76b 23.7 ± 5.59 46.6 ± 25.04b,a 
LFreq/HFreq (nu) 2.79 ± 1.13 0.43 ± 0.29b 3.61 ± 1.18 0.82 ± 0.47 

SDNN, standard deviation of the number of pairs of successive NN (Normal to Normal RR intervals); RMSSD, root mean square of the successive differences; PNN5, the proportion of the number of pairs of successive NN (R-R) intervals that differ by >5 ms divided by the total number of NN (R-R) intervals. In frequency parameters, the measures shown are the normalized power (NORM) for each band (very low frequency, VLFreq; low frequency, LFreq; and high frequency, HFreq) and the ratio of LFreq to Hfreq. Two-way repeated ANOVA followed by Bonferroni test were used. All values are mean ± SD.

a

P < 0.05 versus sham group.

b

P < 0.05 versus the same group under basal conditions.

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