Macroscopic parameters of mice
| Parameter | Sham (n = 12) | HF (n = 12) |
|---|---|---|
| Body parameters | ||
| Lung weight/tibia length Heart weight/tibia length | 9.52 ± 0.87 9.80 ± 0.66 | 15.41 ± 5.26a 16.78 ± 3.64a |
| Echocardiographic data | ||
| FS (%) | 27.62 ± 3.46 | 13.62 ± 3.15a |
| EF (%) | 60.38 ± 5.61 | 33.94 ± 7.03a |
| IVSd (mm) | 0.64 ± 0.10 | 0.65 ± 0.10 |
| IVSs (mm) | 0.92 ± 0.10 | 0.81 ± 0.14a |
| LVIDd (mm) | 3.76 ± 0.38 | 4.44 ± 0.52a |
| LVIDs (mm) | 2.73 ± 0.35 | 3.83 ± 0.48a |
| LVPWd (mm) | 0.68 ± 0.14 | 0.78 ± 0.28 |
| LVPWs (mm) | 0.84 ± 0.10 | 0.86 ± 0.28 |
| LV mass (mg) | 81.60 ± 20.68 | 124.95 ± 65.78a |
| HR (beats/min) | 470 ± 34.64 | 486 ± 38.10 |
| Parameter | Sham | HF |
|---|---|---|
| Lung weight/tibia length | 9.52 ± 0.87 | 15.41 ± 5.26 |
| FS (%) | 27.62 ± 3.46 | 13.62 ± 3.15 |
| EF (%) | 60.38 ± 5.61 | 33.94 ± 7.03 |
| IVSd (mm) | 0.64 ± 0.10 | 0.65 ± 0.10 |
| IVSs (mm) | 0.92 ± 0.10 | 0.81 ± 0.14 |
| LVIDd (mm) | 3.76 ± 0.38 | 4.44 ± 0.52 |
| LVIDs (mm) | 2.73 ± 0.35 | 3.83 ± 0.48 |
| LVPWd (mm) | 0.68 ± 0.14 | 0.78 ± 0.28 |
| LVPWs (mm) | 0.84 ± 0.10 | 0.86 ± 0.28 |
| LV mass (mg) | 81.60 ± 20.68 | 124.95 ± 65.78 |
| HR (beats/min) | 470 ± 34.64 | 486 ± 38.10 |
FS, fractionnal shortening; EF, ejection fraction; IVSd, interventricular septal thickness at end-diastole; IVSs, interventricular septal thickness at end-systole; LVIDd, left ventricular internal dimension at end-diastole; LVIDs, left ventricular internal dimension at end-systole; LVPWd, left ventricular posterior wall thickness at end-diastole; LVPWs, left ventricular posterior wall thickness at end-systole. One-way ANOVA followed by Bonferroni test were used. All the values are mean ± SD.
P < 0.05 versus sham group.
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