Summary of changes (relative to vehicle control) in immune cell populations in the indicated models, treated as indicated. For KC and KCP GEMMs and the orthotopic PDAC model, the G12C-I was ARS and the SHP2-I was SHP099. For Quintana et al. (2020), the SHP2-I was RMC-4630, and for Canon et al. (2019), the G12C-I was AMG510. Only significant changes (P < 0.05) are shown.