Table 1.

Motional mode, compartment size (L), DMACRO, and dwell lifetime (τ) characterizing the hop diffusion of TfR, outside and inside the FA region in the basal PM of T24 cells

Motional Mode (%)Cmpt. Size (L, nm)aDMACRO (µm2/s)aResidency Lifetime (τ, ms)anb
SuppressedSimpleMedian
Mean ± SEM
Histogram Fig. No.c
Median
Mean ± SEM
Histogram Fig. No.
Mean ± SEM
Histogram Fig. No.
TfR (outside FA) 72 28 109
121 ± 6.9#1
Fig. 8 C  
0.12
0.14 ± 0.016#2
Fig. 8 F  
24 ± 1.6#3
Fig. 8 D  
57 
TfR (inside FA) 85 15 74
79 ± 4.2Y1
Fig. 8 C  
0.020
0.046 ± 0.0081Y2
Fig. 8 F  
36 ± 2.8Y3
Fig. 8 D  
54 
Motional Mode (%)Cmpt. Size (L, nm)aDMACRO (µm2/s)aResidency Lifetime (τ, ms)anb
SuppressedSimpleMedian
Mean ± SEM
Histogram Fig. No.c
Median
Mean ± SEM
Histogram Fig. No.
Mean ± SEM
Histogram Fig. No.
TfR (outside FA) 72 28 109
121 ± 6.9#1
Fig. 8 C  
0.12
0.14 ± 0.016#2
Fig. 8 F  
24 ± 1.6#3
Fig. 8 D  
57 
TfR (inside FA) 85 15 74
79 ± 4.2Y1
Fig. 8 C  
0.020
0.046 ± 0.0081Y2
Fig. 8 F  
36 ± 2.8Y3
Fig. 8 D  
54 
a

Cmpt. Size = Compartment size (L). L and DMACRO in the intact PM were estimated by the hop-diffusion fitting. Residency Lifetime (τ) = exponential decay lifetime (mean ± SEM; SEM was determined from the fitting error of the 68.3% confidence interval) within a compartment, based on the residency time distributions obtained by the TILD analysis.

b

The number of inspected molecules.

c

Histogram. Fig. No. = The figure in which the histogram (distribution) is shown.

#, Y, and N are the results of the statistical tests. The distributions selected as the basis for the comparisons are shown by the superscript #. Different numbers indicate different bases for the Brunner-Munzel test (1 and 2) and the log-rank test (3). The superscript Y (or N) with numbers indicates that the distribution is (or is not) significantly different from the base distribution indicated by the number after #, with P values smaller (or greater) than 0.05 as shown: Y1: P = 1.7 × 10−7, Y2: P = 9.3 × 10−9, Y3: P = 4.9 × 10−4.

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