Table 1.

Scores for intermolecular arrangements of CGN and CGNL1 with NM2A, NM2B, and NM2C

Parallel arrangementAntiparallel arrangement
 Stagger Score Overlap Stagger Score Overlap 
CGN-NM2A ND ND ND 421 0.2508 CC50 
CGN-NM2B 440 0.2599 NS 421 0.2508 CC50 
CGN-NM2C 441 0.2364 NS 421 0.2606 CC50 
CGNL1-NM2A 267 NS CN109 304 0.2373 CC72 
CGNL1-NM2B 330 0.2420 CN46 304 0.2442 CC72 
CGNL1-NM2C 326 NS CN50 304 0.2716 CC72 
Parallel arrangementAntiparallel arrangement
 Stagger Score Overlap Stagger Score Overlap 
CGN-NM2A ND ND ND 421 0.2508 CC50 
CGN-NM2B 440 0.2599 NS 421 0.2508 CC50 
CGN-NM2C 441 0.2364 NS 421 0.2606 CC50 
CGNL1-NM2A 267 NS CN109 304 0.2373 CC72 
CGNL1-NM2B 330 0.2420 CN46 304 0.2442 CC72 
CGNL1-NM2C 326 NS CN50 304 0.2716 CC72 

Table shows normalized scores (>0.23) for the total number of potential apolar and ionic interactions are shown as a function of axial stagger and relative orientation between interacting molecules. Scores <0.23 or short overlaps (<32) were NS. ND indicates no score. Axial stagger is designated in terms of the number of residues in a coiled-coil conformation. CC50, for example, indicates molecules overlapping by 50 residues over the C-terminal portion of each of their coiled-coil domains, and CN indicates a C-terminal overlap of CGN or CGNL1 with an N-terminal region of the rod of NM2A, NM2B, or NM2C. Scores were calculated as described in Hulmes et al. (1973); Parry et al. (1977); Fraser et al. (1986).

or Create an Account

Close Modal
Close Modal