Mono- vs. biexponential fit to inactivation kinetics of whole-cell MA currents from DRG neurons
| Imax (pA) . | Monoexponential fit . | Biexponential fit . | ||||
|---|---|---|---|---|---|---|
| τ (ms) | SEM | τ fast (ms) | SEM | τ slow (ms) | SEM | |
| WT | ||||||
| −144.38 | 18.91 | 0.16 | 11.28 | 0.16 | 332.25 | 77.45 |
| −251.66 | 25.23 | 0.13 | 16.79 | 1.10 | 47.44 | 6.51 |
| −175.25 | 9.02 | 0.08 | 2.89 | 0.08 | 17.76 | 0.38 |
| −159.12 | 16.52 | 0.15 | 8.49 | 0.14 | 121.31 | 13.32 |
| −157.10 | 40.39 | 0.80 | 2.67 | 0.15 | 64.13 | 2.33 |
| Npy2r | ||||||
| −2872.13 | 9.18 | 0.13 | 9.18 | 0.04 | 79.22 | 5.48 |
| −1445.08 | 15.47 | 0.07 | 18.14 | 0.05 | 470.29 | 76.85 |
| −2941.61 | 28.96 | 0.06 | 7.98 | 0.44 | 26.26 | 0.16 |
| −3863.31 | 24.22 | 0.15 | 12.74 | 0.06 | 33.24 | 0.10 |
| HoxB8-Cre;Piezo2f/− | ||||||
| −145.61 | 31.32 | 0.12 | 1.95 | 0.15 | 35.99 | 0.36 |
| Imax (pA) . | Monoexponential fit . | Biexponential fit . | ||||
|---|---|---|---|---|---|---|
| τ (ms) | SEM | τ fast (ms) | SEM | τ slow (ms) | SEM | |
| WT | ||||||
| −144.38 | 18.91 | 0.16 | 11.28 | 0.16 | 332.25 | 77.45 |
| −251.66 | 25.23 | 0.13 | 16.79 | 1.10 | 47.44 | 6.51 |
| −175.25 | 9.02 | 0.08 | 2.89 | 0.08 | 17.76 | 0.38 |
| −159.12 | 16.52 | 0.15 | 8.49 | 0.14 | 121.31 | 13.32 |
| −157.10 | 40.39 | 0.80 | 2.67 | 0.15 | 64.13 | 2.33 |
| Npy2r | ||||||
| −2872.13 | 9.18 | 0.13 | 9.18 | 0.04 | 79.22 | 5.48 |
| −1445.08 | 15.47 | 0.07 | 18.14 | 0.05 | 470.29 | 76.85 |
| −2941.61 | 28.96 | 0.06 | 7.98 | 0.44 | 26.26 | 0.16 |
| −3863.31 | 24.22 | 0.15 | 12.74 | 0.06 | 33.24 | 0.10 |
| HoxB8-Cre;Piezo2f/− | ||||||
| −145.61 | 31.32 | 0.12 | 1.95 | 0.15 | 35.99 | 0.36 |