Table 1.

Top hits from the ERK7 interactome

Known localization
Y2HBioIDGene IDGene nameLocalization
✓ ✓ TG*_246950 AC9 Apical cap (Chen et al., 2017; Tosetti et al., 2020; Back et al., 2022) 
✓ ✓ TG*_292950 AC10 Apical cap (Tosetti et al., 2020; Back et al., 2022) 
 ✓ TG*_250820 AC2 Apical cap (Beck et al., 2010) 
 ✓ TG*_214880 AC4 Apical cap (Beck et al., 2010) 
 ✓ TG*_229640 AC8 Apical cap (Chen et al., 2017) 
 ✓ TG*_310030 TgCAP Apical cap (Lorestani et al., 2012; Hunt et al., 2019) 
 ✓ TG*_310930 TgFBXO1 IMC (Baptista et al., 2019) 
 ✓ TG*_316540 ISP3 IMC(Beck et al., 2010) 
 ✓ TG*_231640 IMC1 IMC (Mann and Beckers, 2001; Wichroski et al., 2002) 
 ✓ TG*_231630 IMC4 IMC (Hu et al., 2006) 
 ✓ TG*_230210 IMC10 IMC (Gould et al., 2008; Anderson-White et al., 2011) 
 ✓ TG*_235340 ISC1 IMC (Beck et al., 2010) 
 ✓ TG*_252880 CRMP Conoid (Gould et al., 2011) 
 ✓ TG*_246720a Hypothetical Conoid (Hu et al., 2006) 
✓ ✓ TG*_239885 Prot. Kinase Unknown (Smith et al., 2022) 
Localized in this study 
Y2H BioID Gene ID Gene name Localization 
✓ ✓ TG*_238380 Hypothetical Apical cap 
✓ ✓ TG*_285140 Hypothetical Apical dot 
✓  TG*_236060 Hypothetical Cytosolic/apical cap 
✓  TG*_260500b Hypothetical IMC sutures 
 ✓ TG*_231210b Epsin-like Apical/endosomal? 
 ✓ TG*_309560b Bax-like Apical/endosomal? 
✓  TG*_315950 CSAR1 Residual body (-IAA)/apical cap (+IAA) 
Known localization
Y2HBioIDGene IDGene nameLocalization
✓ ✓ TG*_246950 AC9 Apical cap (Chen et al., 2017; Tosetti et al., 2020; Back et al., 2022) 
✓ ✓ TG*_292950 AC10 Apical cap (Tosetti et al., 2020; Back et al., 2022) 
 ✓ TG*_250820 AC2 Apical cap (Beck et al., 2010) 
 ✓ TG*_214880 AC4 Apical cap (Beck et al., 2010) 
 ✓ TG*_229640 AC8 Apical cap (Chen et al., 2017) 
 ✓ TG*_310030 TgCAP Apical cap (Lorestani et al., 2012; Hunt et al., 2019) 
 ✓ TG*_310930 TgFBXO1 IMC (Baptista et al., 2019) 
 ✓ TG*_316540 ISP3 IMC(Beck et al., 2010) 
 ✓ TG*_231640 IMC1 IMC (Mann and Beckers, 2001; Wichroski et al., 2002) 
 ✓ TG*_231630 IMC4 IMC (Hu et al., 2006) 
 ✓ TG*_230210 IMC10 IMC (Gould et al., 2008; Anderson-White et al., 2011) 
 ✓ TG*_235340 ISC1 IMC (Beck et al., 2010) 
 ✓ TG*_252880 CRMP Conoid (Gould et al., 2011) 
 ✓ TG*_246720a Hypothetical Conoid (Hu et al., 2006) 
✓ ✓ TG*_239885 Prot. Kinase Unknown (Smith et al., 2022) 
Localized in this study 
Y2H BioID Gene ID Gene name Localization 
✓ ✓ TG*_238380 Hypothetical Apical cap 
✓ ✓ TG*_285140 Hypothetical Apical dot 
✓  TG*_236060 Hypothetical Cytosolic/apical cap 
✓  TG*_260500b Hypothetical IMC sutures 
 ✓ TG*_231210b Epsin-like Apical/endosomal? 
 ✓ TG*_309560b Bax-like Apical/endosomal? 
✓  TG*_315950 CSAR1 Residual body (-IAA)/apical cap (+IAA) 
a

Previously identified at conoid by proximity biotinylation (Long et al., 2017).

b

Previously identified in published conoid proteome (Hu et al., 2006).

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