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Table 1.
Steady-state activation and inactivation parameters of ICaL in the absence and presence of 10 µM phenanthrene (Phe)
ActivationInactivation
Control10 µM PheControl10 µM Phe
V0.5 −23.6 ± 1.3 mV −24.9 ± 1.1 mV −31.8 ± 0.1 mV −32.0 ± 0.1 mV 
5.1 ± 0.2 5.1 ± 0.2 1.4 ± 0.2 1.1 ± 0.1 
ActivationInactivation
Control10 µM PheControl10 µM Phe
V0.5 −23.6 ± 1.3 mV −24.9 ± 1.1 mV −31.8 ± 0.1 mV −32.0 ± 0.1 mV 
5.1 ± 0.2 5.1 ± 0.2 1.4 ± 0.2 1.1 ± 0.1 

Parameters were obtained by fitting with Boltzman equation of individual activation (G/Gmax) and inactivation (I/Imax) curves as described in Materials and methods. V0.5, half-maximal voltage of activation and inactivation; k, slope factor. All values are presented as means ± SEM (n = 6; N = 2).

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