Table 5.

Parameter
. | Description
. | Value
. |
---|---|---|

r_{0} | Width of energy potential well characterizing the length of tubulin–tubulin bond | 0.13 nm |

a_{lat} | Energy parameter for lateral repulsion; corresponds with ∼2 × height of the energy barrier for lateral bond | 15 k_{B}T = 9 kcal/mol |

b_{lat} | Depth of the potential well for lateral bonds | 5.3 k_{B}T = 3.2 kcal/mol for MT growth |

4.3 k_{B}T = 2.6 kcal/mol for MT shortening | ||

a_{long} | Energy parameter for longitudinal repulsion; corresponds with ∼2 × height of the energy barrier for longitudinal interdimer bond | 15 k_{B}T = 9 kcal/mol |

b_{long} | Depth of the potential well for longitudinal interdimer bond | 16.6 k_{B}T = 10 kcal/mol |

k | Stiffness of longitudinal intradimer bond | 517 k_{B}T nm^{−2} = 310 kcal/mol nm^{−2} |

B | Flexural rigidity of PF bending | 58 k_{B}T rad^{−2} = 35 kcal/mol rad^{−2} |

χ^{D}_{0} | Equilibrium angle between GDP-tubulin monomers | 0.2 rad |

χ^{T}_{0} | Equilibrium angle between GTP-tubulin monomers | 0.2 rad |

c_{tub} | Soluble tubulin concentration | 10 µM |

k_{on} | On-rate constant for tubulin addition | 8.3 µM^{−1}s^{−1} per MT |

T | Temperature | 310 K |

η | Viscosity | 0.2 Pa · s |

dt | time step for dynamic algorithm | 10^{−10} s |

T_{kin} | time step for kinetic algorithm | 10^{−3} s |

Parameter
. | Description
. | Value
. |
---|---|---|

r_{0} | Width of energy potential well characterizing the length of tubulin–tubulin bond | 0.13 nm |

a_{lat} | Energy parameter for lateral repulsion; corresponds with ∼2 × height of the energy barrier for lateral bond | 15 k_{B}T = 9 kcal/mol |

b_{lat} | Depth of the potential well for lateral bonds | 5.3 k_{B}T = 3.2 kcal/mol for MT growth |

4.3 k_{B}T = 2.6 kcal/mol for MT shortening | ||

a_{long} | Energy parameter for longitudinal repulsion; corresponds with ∼2 × height of the energy barrier for longitudinal interdimer bond | 15 k_{B}T = 9 kcal/mol |

b_{long} | Depth of the potential well for longitudinal interdimer bond | 16.6 k_{B}T = 10 kcal/mol |

k | Stiffness of longitudinal intradimer bond | 517 k_{B}T nm^{−2} = 310 kcal/mol nm^{−2} |

B | Flexural rigidity of PF bending | 58 k_{B}T rad^{−2} = 35 kcal/mol rad^{−2} |

χ^{D}_{0} | Equilibrium angle between GDP-tubulin monomers | 0.2 rad |

χ^{T}_{0} | Equilibrium angle between GTP-tubulin monomers | 0.2 rad |

c_{tub} | Soluble tubulin concentration | 10 µM |

k_{on} | On-rate constant for tubulin addition | 8.3 µM^{−1}s^{−1} per MT |

T | Temperature | 310 K |

η | Viscosity | 0.2 Pa · s |

dt | time step for dynamic algorithm | 10^{−10} s |

T_{kin} | time step for kinetic algorithm | 10^{−3} s |

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