The persistence of filopods increases in N-WASP/WAVE2 KD cells
. | Persistence (s) . | . | |
|---|---|---|---|
. | Scr . | N-WASP/WAVE2 . | |
| Mean | 111.38 | 139.13 | |
| SEM | 8.52 | 5.42 | |
. | Persistence (s) . | . | |
|---|---|---|---|
. | Scr . | N-WASP/WAVE2 . | |
| Mean | 111.38 | 139.13 | |
| SEM | 8.52 | 5.42 | |
Cells were treated with either scrambled (Scr) or N-WASP and WAVE2 siRNA. Filopod length was quantified from time-lapse videos after EGF stimulation. Persistence was measured by lifetime of filopods throughout EGF stimulation. Lifetime is defined as the total duration of a filopod from first appearance to final disappearance in the time-lapse movie. P-values are in comparison to control. P = 1.73 × 10−5.