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Table I.

Membrane-free p62-positive aggregates accumulate in ESCRT depleted cells


Aggregates per cell ± SD
Control 0 ± 0 
Tsg101 siRNA 0.095 ± 0.037* 
Vps 24 siRNA 0.100 ± 0.050* 

Aggregates per cell ± SD
Control 0 ± 0 
Tsg101 siRNA 0.095 ± 0.037* 
Vps 24 siRNA 0.100 ± 0.050* 

The number of p62-positive aggregates in control, Tsg101, and Vps24 siRNA treated cells was quantified by counting approximately 200 randomly chosen cell profiles per group from 3 different experiments. *, P ≤ 0.05 according to t test.

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