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Table I.

EMT markers


Proteins that increase in abundance 
    N-cadherin 
    Vimentin 
    Fibronectin 
    Snail1 (Snail) 
    Snail2 (Slug) 
    Twist 
    Goosecoid 
    FOXC2 
    Sox10 
    MMP-2 
    MMP-3 
    MMP-9 
    Integrin αvβ6 
Proteins that decrease in abundance 
    E-cadherin 
    Desmoplakin 
    Cytokeratin 
    Occludin 
Proteins whose activity increases 
    ILK 
    GSK-3β 
    Rho 
Proteins that accumulate in the nucleus 
    β-catenin 
    Smad-2/3 
    NF-κβ 
    Snail1 (Snail) 
    Snail2 (Slug) 
    Twist 
In vitro functional markers 
    Increased migration 
    Increased invasion 
    Increased scattering 
    Elongation of cell shape 
    Resistance to anoikis
 

Proteins that increase in abundance 
    N-cadherin 
    Vimentin 
    Fibronectin 
    Snail1 (Snail) 
    Snail2 (Slug) 
    Twist 
    Goosecoid 
    FOXC2 
    Sox10 
    MMP-2 
    MMP-3 
    MMP-9 
    Integrin αvβ6 
Proteins that decrease in abundance 
    E-cadherin 
    Desmoplakin 
    Cytokeratin 
    Occludin 
Proteins whose activity increases 
    ILK 
    GSK-3β 
    Rho 
Proteins that accumulate in the nucleus 
    β-catenin 
    Smad-2/3 
    NF-κβ 
    Snail1 (Snail) 
    Snail2 (Slug) 
    Twist 
In vitro functional markers 
    Increased migration 
    Increased invasion 
    Increased scattering 
    Elongation of cell shape 
    Resistance to anoikis
 
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