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Table III.

Cell-type dependence of the extent of calcium induced lysosomal exocytosis


Cell type

Treatment

Fraction of peripheral lysosomes that exocytose
  n = cells 
NRK A23187 with 1.2 mM extracellular calcium 7 ± 1% (n = 21) 
CHO A23187 with 1.2 mM extracellular calcium 5 ± 1% (n = 8) 
WM239 A23187 with 1.2 mM extracellular calcium  <2% (n = 4) 
HeLa A23187 with 1.2 mM or 2 mM extracellular calcium 0% (n = 8) 
HeLa A23187 with 5 mM or 10 mM extracellular calcium 4 ± 0.8% (n = 4) 
Murine embryonic primary fibroblast
 
A23187 with 1.2 mM extracellular calcium
 
24 ± 6% (n = 6)
 

Cell type

Treatment

Fraction of peripheral lysosomes that exocytose
  n = cells 
NRK A23187 with 1.2 mM extracellular calcium 7 ± 1% (n = 21) 
CHO A23187 with 1.2 mM extracellular calcium 5 ± 1% (n = 8) 
WM239 A23187 with 1.2 mM extracellular calcium  <2% (n = 4) 
HeLa A23187 with 1.2 mM or 2 mM extracellular calcium 0% (n = 8) 
HeLa A23187 with 5 mM or 10 mM extracellular calcium 4 ± 0.8% (n = 4) 
Murine embryonic primary fibroblast
 
A23187 with 1.2 mM extracellular calcium
 
24 ± 6% (n = 6)
 
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