Distinct effects of micro-CALI of M1c and MII on the proportion of protruding lamellipodia
Lamellipodial behavior . | Protrusion . | Retraction . | Stationary . | ||
|---|---|---|---|---|---|
| % | |||||
| IgG control | 74.9 ± 7.7 (9) | 20.8 ± 6.7 (9) | 4.2 ± 2.1 (9) | ||
| M1c | 60.4 ± 8.8 (10) | 31.3 ± 7.9 (10) | 6.7 ± 2.7 (10) | ||
| MII | 46.4 ± 10.7 (9)a | 39.6 ± 9.8 (9) | 12.5 ± 2.8 (9)a | ||
Lamellipodial behavior . | Protrusion . | Retraction . | Stationary . | ||
|---|---|---|---|---|---|
| % | |||||
| IgG control | 74.9 ± 7.7 (9) | 20.8 ± 6.7 (9) | 4.2 ± 2.1 (9) | ||
| M1c | 60.4 ± 8.8 (10) | 31.3 ± 7.9 (10) | 6.7 ± 2.7 (10) | ||
| MII | 46.4 ± 10.7 (9)a | 39.6 ± 9.8 (9) | 12.5 ± 2.8 (9)a | ||
Significant difference relative to IgG control (P < 0.05).
For lamellipodial behavior, the proportions of protruding, retracting, and stationary lamellipodia were determined and expressed as the percentage of the total number of lamellipodia for that group. Numbers in parentheses indicate the number of growth cones.