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Table 1

Nuclear Foci Formed in Synchronized Human Fibroblasts

Percentage of nuclei with >10 foci containing:
Cell cycle positionPMLBLMRAD51RP-APML+BLMPML+RAD51PML+BLM+RAD51
G0 >95 <10 30 <1 <10 30 <1 
Late S/G2 >95 >50 30–40 10–20 >50 30–40 15–20 
Percentage of nuclei with >10 foci containing:
Cell cycle positionPMLBLMRAD51RP-APML+BLMPML+RAD51PML+BLM+RAD51
G0 >95 <10 30 <1 <10 30 <1 
Late S/G2 >95 >50 30–40 10–20 >50 30–40 15–20 

WI-38 cells were synchronized, and the PML, BLM, hRAD51, and RP-A proteins were detected by immunofluorescence as described in Materials and Methods.

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